The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation.
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Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domainsNeural KCNQ (Kv7) channelsKCNQ potassium channels in sensory system and neural circuitsHomeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potentialMultiple chronic pain states are associated with a common amino acid-changing allele in KCNS1Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats.Visceral hyperalgesia induced by forebrain-specific suppression of native Kv7/KCNQ/M-current in mice.Kv7.2 regulates the function of peripheral sensory neurons.Kv7.5 is the primary Kv7 subunit expressed in C-fibers.Antidystonic effects of Kv7 (KCNQ) channel openers in the dt sz mutant, an animal model of primary paroxysmal dystoniaEmerging analgesics in cancer pain management.Retigabine.Breaking barriers to novel analgesic drug development.Noise-induced hearing loss: Neuropathic pain via Ntrk1 signalingAnalgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin.Kv2 dysfunction after peripheral axotomy enhances sensory neuron responsiveness to sustained input.Activation of peripheral KCNQ channels attenuates inflammatory pain.Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury.Endothelin-1 raises excitability and reduces potassium currents in sensory neurons.Enhancing m currents: a way out for neuropathic pain?Possible involvement of nitric oxide modulatory mechanism in the protective effect of retigabine against spinal nerve ligation-induced neuropathic pain.KCNQ/Kv7 channel regulation of hippocampal gamma-frequency firing in the absence of synaptic transmission.Endothelin-1 Decreases Excitability of the Dorsal Root Ganglion Neurons via ETB Receptor.
P2860
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P2860
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
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2004年学术文章
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2004年學術文章
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name
The anti-hyperalgesic activity ...... potassium channel activation.
@en
The anti-hyperalgesic activity ...... potassium channel activation.
@nl
type
label
The anti-hyperalgesic activity ...... potassium channel activation.
@en
The anti-hyperalgesic activity ...... potassium channel activation.
@nl
prefLabel
The anti-hyperalgesic activity ...... potassium channel activation.
@en
The anti-hyperalgesic activity ...... potassium channel activation.
@nl
P2093
P1476
The anti-hyperalgesic activity ...... potassium channel activation.
@en
P2093
P2888
P304
P356
10.1007/S00210-004-0881-1
P577
2004-03-09T00:00:00Z