De novo ceramide accumulation due to inhibition of its conversion to complex sphingolipids in apoptotic photosensitized cells.
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Mammalian ceramide synthasesRoles of bioactive sphingolipids in cancer biology and therapeuticsSphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamageThe impact of sphingosine kinase-1 in head and neck cancer.Increased ceramide accumulation correlates with downregulation of the autophagy protein ATG-7 in MCF-7 cells sensitized to photodamage.Mechanisms in photodynamic therapy: part two-cellular signaling, cell metabolism and modes of cell deathAmplification of cancer cell apoptosis in photodynamic therapy-treated tumors by adjuvant ceramide analog LCL29.Ceramide response post-photodamage is absent after treatment with HA14-1C16-Ceramide Analog Combined with Pc 4 Photodynamic Therapy Evokes Enhanced Total Ceramide Accumulation, Promotion of DEVDase Activation in the Absence of Apoptosis, and Augmented Overall Cell KillingCombining anticancer agents photodynamic therapy and LCL85 leads to distinct changes in the sphingolipid profile, autophagy, caspase-3 activation in the absence of cell death, and long-term sensitizationEnhanced killing of SCC17B human head and neck squamous cell carcinoma cells after photodynamic therapy plus fenretinide via the de novo sphingolipid biosynthesis pathway and apoptosisEnhanced tumor cures after Foscan photodynamic therapy combined with the ceramide analog LCL29. Evidence from mouse squamous cell carcinomas for sphingolipids as biomarkers of treatment response.Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway.C6-pyridinium ceramide sensitizes SCC17B human head and neck squamous cell carcinoma cells to photodynamic therapyEosinophil activation of fibroblasts from chronic allergen-induced disease utilizes stem cell factor for phenotypic changes.Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamageIncreased tumour dihydroceramide production after Photofrin-PDT alone and improved tumour response after the combination with the ceramide analogue LCL29. Evidence from mouse squamous cell carcinomas.Cationic ceramides and analogues, LCL30 and LCL85, as adjuvants to photodynamic therapy of tumors.Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis.Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation.Electroporation-mediated delivery of the FER gene in the resolution of trauma-related fatal pneumonia.Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cellssiRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy.Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance.Sphingolipids: key regulators of apoptosis and pivotal players in cancer drug resistanceCeramide synthases in mammalians, worms, and insects: emerging schemes.Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.Enhanced apoptotic cancer cell killing after Foscan photodynamic therapy combined with fenretinide via de novo sphingolipid biosynthesis pathway.Ethanol-induced changes in the content of triglycerides, ceramides, and glucosylceramides in cultured neurons.Ceramide phosphoethanolamine synthase SMSr is a target of caspase-6 during apoptotic cell death.Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System.Monitoring Changes in the Oligomeric State of a Candidate Endoplasmic Reticulum (ER) Ceramide Sensor by Single-molecule Photobleaching.
P2860
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P2860
De novo ceramide accumulation due to inhibition of its conversion to complex sphingolipids in apoptotic photosensitized cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
De novo ceramide accumulation ...... optotic photosensitized cells.
@en
De novo ceramide accumulation ...... optotic photosensitized cells.
@nl
type
label
De novo ceramide accumulation ...... optotic photosensitized cells.
@en
De novo ceramide accumulation ...... optotic photosensitized cells.
@nl
prefLabel
De novo ceramide accumulation ...... optotic photosensitized cells.
@en
De novo ceramide accumulation ...... optotic photosensitized cells.
@nl
P2093
P2860
P356
P1476
De novo ceramide accumulation ...... poptotic photosensitized cells
@en
P2093
Biserka Nagy
Duska Separovic
Kentaro Hanada
M Sharjeel Farooqui
Olga I Kulaeva
Vladislav Dolgachev
P2860
P304
23238-23249
P356
10.1074/JBC.M311974200
P407
P50
P577
2004-03-12T00:00:00Z