Retargeted clostridial endopeptidases: inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain.
about
Structures of engineeredClostridium botulinumneurotoxin derivativesThe C-terminal heavy-chain domain of botulinum neurotoxin a is not the only site that binds neurons, as the N-terminal heavy-chain domain also plays a very active role in toxin-cell binding and interactions.Towards new uses of botulinum toxin as a novel therapeutic toolClinical uses of botulinum neurotoxins: current indications, limitations and future developmentsBotulinum neurotoxin structure, engineering, and novel cellular trafficking and targeting.Engineering botulinum neurotoxin to extend therapeutic intervention.Anti-nociceptive effect of a conjugate of substance P and light chain of botulinum neurotoxin type ATreatment of refractory pain with botulinum toxins--an evidence-based review.Targeted secretion inhibitors-innovative protein therapeuticsBotulinum neurotoxin for pain management: insights from animal models.Clostridial neurotoxins: mechanism of SNARE cleavage and outlook on potential substrate specificity reengineering.More than at the neuromuscular synapse: actions of botulinum neurotoxin A in the central nervous system.Stapling of the botulinum type A protease to growth factors and neuropeptides allows selective targeting of neuroendocrine cellsBotulinum Neurotoxins: Biology, Pharmacology, and Toxicology.Behavioral and structural effects of unilateral intrastriatal injections of botulinum neurotoxin a in the rat model of Parkinson's disease.Re-engineering the target specificity of Clostridial neurotoxins - a route to novel therapeutics.Engineering botulinum neurotoxin domains for activation by toxin light chain.Experimental Intrastriatal Applications of Botulinum Neurotoxin-A: A Review.
P2860
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P2860
Retargeted clostridial endopeptidases: inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Retargeted clostridial endopep ...... ity in in vivo models of pain.
@en
Retargeted clostridial endopep ...... ity in in vivo models of pain.
@nl
type
label
Retargeted clostridial endopep ...... ity in in vivo models of pain.
@en
Retargeted clostridial endopep ...... ity in in vivo models of pain.
@nl
prefLabel
Retargeted clostridial endopep ...... ity in in vivo models of pain.
@en
Retargeted clostridial endopep ...... ity in in vivo models of pain.
@nl
P2093
P356
P1433
P1476
Retargeted clostridial endopep ...... ity in in vivo models of pain.
@en
P2093
Anthony Dickenson
Clifford C Shone
Elizabeth R Kirby
Frances C G Alexander
G Mark Green
Hilary J Moulsdale
John A Chaddock
John R Purkiss
Keith A Foster
Lorna M Friis
P356
10.1002/MDS.20008
P407
P478
19 Suppl 8
P577
2004-03-01T00:00:00Z