Biosynthetic origin of the rare nitroaryl moiety of the polyketide antibiotic aureothin: involvement of an unprecedented N-oxygenase.
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Nitroaromatic compounds, from synthesis to biodegradationBiosynthesis of oxygen and nitrogen-containing heterocycles in polyketidesIn vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesisCloning and characterization of the pyrrolomycin biosynthetic gene clusters from Actinosporangium vitaminophilum ATCC 31673 and Streptomyces sp. strain UC 11065Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues.An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesisFour-electron oxidation of p-hydroxylaminobenzoate to p-nitrobenzoate by a peroxodiferric complex in AurF from Streptomyces thioluteus.Novel compounds produced by Streptomyces lydicus NRRL 2433 engineered mutants altered in the biosynthesis of streptolydigin.Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic origin.Probing the substrate specificity of aminopyrrolnitrin oxygenase (PrnD) by mutational analysis.Synthesis and biological characterization of arylomycin B antibioticsNovel Approaches for the Accumulation of Oxygenated Intermediates to Multi-Millimolar Concentrations.Naturally-occurring nitro compounds.Recent advances in the biosynthesis of unusual polyketide synthase substrates.Nitropyrrole natural products: isolation, biosynthesis and total synthesis.Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents.Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.Mutational analysis of nocK and nocL in the nocardicin a producer Nocardia uniformis.A unifying nitrososynthase involved in nitrosugar biosynthesis.Mechanism for Six-Electron Aryl-N-Oxygenation by the Non-Heme Diiron Enzyme CmlI.An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway.Characterization of the flavoenzyme XiaK as an N-hydroxylase and implications in indolosesquiterpene diversification.Multifactorial control of iteration events in a modular polyketide assembly line.Reconstitution and characterization of aminopyrrolnitrin oxygenase, a Rieske N-oxygenase that catalyzes unusual arylamine oxidation.Five nitro-phenyl compounds from the South China Sea mangrove fungus.CmlI N-Oxygenase Catalyzes the Final Three Steps in Chloramphenicol Biosynthesis without Dissociation of Intermediates.Identification and characterization of a bacterial cytochrome P450 monooxygenase catalyzing the 3-nitration of tyrosine in rufomycin biosynthesis.Dissection of the late steps in aureothin biosynthesis.Warhead biosynthesis and the origin of structural diversity in hydroxamate metalloproteinase inhibitors.A new class of arylamine oxygenases: evidence that p-aminobenzoate N-oxygenase (AurF) is a di-iron enzyme and further mechanistic studies.Diiron monooxygenases in natural product biosynthesis.Biosynthesis of fragin is controlled by a novel quorum sensing signal.A ribonucleotide reductase-like electron transfer system in the nitroaryl-forming N-oxygenase AurF.Natural products chemistry: The emerging trends and prospective goals.Convergent Asymmetric Synthesis of (+)-Aureothin Employing an Oxygenase-Mediated Resolution Step
P2860
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P2860
Biosynthetic origin of the rare nitroaryl moiety of the polyketide antibiotic aureothin: involvement of an unprecedented N-oxygenase.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Biosynthetic origin of the rar ...... an unprecedented N-oxygenase.
@en
Biosynthetic origin of the rar ...... an unprecedented N-oxygenase.
@nl
type
label
Biosynthetic origin of the rar ...... an unprecedented N-oxygenase.
@en
Biosynthetic origin of the rar ...... an unprecedented N-oxygenase.
@nl
prefLabel
Biosynthetic origin of the rar ...... an unprecedented N-oxygenase.
@en
Biosynthetic origin of the rar ...... an unprecedented N-oxygenase.
@nl
P921
P356
P1476
Biosynthetic origin of the rar ...... an unprecedented N-oxygenase.
@en
P2093
P304
P356
10.1021/JA039328T
P407
P577
2004-03-01T00:00:00Z