Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonist.

Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonist.

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http://www.wikidata.org/entity/Q44823652
Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertensionStructure-activity relationship studies of the tricyclic indoline resistance-modifying agent.Selective endothelin-1 receptor type A inhibition in subjects undergoing cardiac surgery with preexisting left ventricular dysfunction: Influence on early postoperative hemodynamics.Endothelin receptor A antagonism attenuates renal medullary blood flow impairment in endotoxemic pigs.The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house?Vasoactive peptides in cardiovascular (patho)physiology.Optimizing endothelin receptor antagonist use in the management of pulmonary arterial hypertension.Leads for the treatment of pulmonary hypertension.A facile and convenient synthesis of some novel hydrazones, Schiff's base and pyrazoles incorporating thieno[2,3-b]thiophenesBosentan for pulmonary hypertension and other pulmonary diseases: emerging evidence.DBU-mediated [4 + 1] annulations of donor-acceptor cyclopropanes with carbon disulfide or thiourea for synthesis of 2-aminothiophene-3-carboxylates.
P2860

Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonist.

Item
http://www.wikidata.org/entity/Q44823652
description
2004 nî lūn-bûn
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2004年の論文
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name
Discovery, modeling, and human ...... ailable endothelin antagonist.
@en
Discovery, modeling, and human ...... ailable endothelin antagonist.
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type
label
Discovery, modeling, and human ...... ailable endothelin antagonist.
@en
Discovery, modeling, and human ...... ailable endothelin antagonist.
@nl
prefLabel
Discovery, modeling, and human ...... ailable endothelin antagonist.
@en
Discovery, modeling, and human ...... ailable endothelin antagonist.
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P1433
P1476
P2093
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P433
P478
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P1433
P1476
Discovery, modeling, and human ...... ailable endothelin antagonist.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698