Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential.
about
ChannelopathiesSalinomycin: a novel anti-cancer agent with known anti-coccidial activitiesIon channels and apoptosis in cancerVoltage-gated ion channels in cancer cell proliferationTargeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide.A whole-genome RNAi screen uncovers a novel role for human potassium channels in cell killing by the parasite Entamoeba histolyticaEpigenetic dysregulation of KCa 3.1 channels induces poor prognosis in lung cancer.Epigenetic deregulation in pediatric acute lymphoblastic leukemia.Big Potassium (BK) ion channels in biology, disease and possible targets for cancer immunotherapy.Efficacy of a hypotonic treatment for peritoneal dissemination from gastric cancer cells: an in vivo evaluationGlycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer questionCancer as a channelopathy: ion channels and pumps in tumor development and progressionhERG1 channels drive tumour malignancy and may serve as prognostic factor in pancreatic ductal adenocarcinoma.ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration.Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer.Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers.Regulation of osmolality for cancer treatment.Knockdown of the small conductance Ca(2+) -activated K(+) channels is potently cytotoxic in breast cancer cell lines.Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment.Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cellsCFTR is a tumor suppressor gene in murine and human intestinal cancerCariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research.Expression profiling of ion channel genes predicts clinical outcome in breast cancer.Ion channel gene expression in lung adenocarcinoma: potential role in prognosis and diagnosis.Ion channels or aquaporins as novel molecular targets in gastric cancer.Regulation and roles of bicarbonate transporters in cancer.Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment.Regulation of voltage-gated sodium channel expression in cancer: hormones, growth factors and auto-regulation.TRP channels and STIM/ORAI proteins: sensors and effectors of cancer and stroma cell migrationCellular physiological approach for treatment of gastric cancer.Discovery of functional antibodies targeting ion channels.A unique epigenetic signature is associated with active DNA replication loci in human embryonic stem cells.Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1.ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca2+/RhoA pathway.Gene regulatory mechanisms underpinning prostate cancer susceptibility.Promoter Methylation Analysis Reveals That KCNA5 Ion Channel Silencing Supports Ewing Sarcoma Cell Proliferation.Cancer cell behaviors mediated by dysregulated pH dynamics at a glance.Resveratrol: inhibitory effects on metastatic cell behaviors and voltage-gated Na⁺ channel activity in rat prostate cancer in vitro.Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane.
P2860
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P2860
Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Ion channels and transporters ...... ation, and clinical potential.
@en
Ion channels and transporters ...... ation, and clinical potential.
@nl
type
label
Ion channels and transporters ...... ation, and clinical potential.
@en
Ion channels and transporters ...... ation, and clinical potential.
@nl
prefLabel
Ion channels and transporters ...... ation, and clinical potential.
@en
Ion channels and transporters ...... ation, and clinical potential.
@nl
P1433
P1476
Ion channels and transporters ...... ation, and clinical potential.
@en
P2093
Christian Stock
P304
P356
10.1158/0008-5472.CAN-12-4188
P407
P577
2013-01-09T00:00:00Z