Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
about
Thalidomide-induced limb abnormalities in a humanized CYP3A mouse modelCombining Chimeric Mice with Humanized Liver, Mass Spectrometry, and Physiologically-Based Pharmacokinetic Modeling in Toxicology.Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform.In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice.Human cytochrome P450 oxidation of 5-hydroxythalidomide and pomalidomide, an amino analogue of thalidomide.Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate.In vivo formation of a glutathione conjugate derived from thalidomide in humanized uPA-NOG mice.The Dihydroxy Metabolite of the Teratogen Thalidomide Causes Oxidative DNA Damage.LC-MS/MS and chiroptical spectroscopic analyses of multidimensional metabolic systems of chiral thalidomide and its derivatives.Thalidomide Embryopathy: An Enigmatic Challenge
P2860
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P2860
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
@en
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
@nl
type
label
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
@en
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
@nl
prefLabel
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
@en
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
@nl
P2093
P50
P356
P1476
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans.
@en
P2093
Brian D Palmer
Bruce C Baguley
Lai-Ming Ching
Philip Kestell
P304
P356
10.1124/JPET.104.067793
P407
P577
2004-04-09T00:00:00Z