Characterization of the preferred stereochemistry for the neuropharmacologic actions of antillatoxin.
about
Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 α subunitsAntillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channelsConcise synthesis and biological assessment of (+)-neopeltolide and a 16-member stereoisomer library of 8,9-dehydroneopeltolide: identification of pharmacophoric elements.The twisted side chain of antillatoxin is important for potent toxicity: total synthesis and biological evaluation of antillatoxin and analogues.Shellfish toxins targeting voltage-gated sodium channels.Recent progress in neuroactive marine natural products.Total synthesis and functional analysis of non-ribosomal peptides.A review of pharmacological and toxicological potentials of marine cyanobacterial metabolites.The bulky side chain of antillatoxin is important for potent toxicity: rational design of photoresponsive cytotoxins based on SAR studies.
P2860
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P2860
Characterization of the preferred stereochemistry for the neuropharmacologic actions of antillatoxin.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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name
Characterization of the prefer ...... logic actions of antillatoxin.
@en
Characterization of the prefer ...... logic actions of antillatoxin.
@nl
type
label
Characterization of the prefer ...... logic actions of antillatoxin.
@en
Characterization of the prefer ...... logic actions of antillatoxin.
@nl
prefLabel
Characterization of the prefer ...... logic actions of antillatoxin.
@en
Characterization of the prefer ...... logic actions of antillatoxin.
@nl
P2093
P356
P1476
Characterization of the prefer ...... logic actions of antillatoxin.
@en
P2093
B L Marquez
F Yokokawa
T F Murray
W H Gerwick
P304
P356
10.1021/NP0303409
P577
2004-04-01T00:00:00Z