Endothelin stimulates endothelial nitric oxide synthase expression in the thick ascending limb.
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Tumor necrosis factor α decreases nitric oxide synthase type 3 expression primarily via Rho/Rho kinase in the thick ascending limbAngiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbsAngiotensin II stimulates thick ascending limb NO production via AT(2) receptors and Akt1-dependent nitric-oxide synthase 3 (NOS3) activationAngiotensin II stimulates thick ascending limb superoxide production via protein kinase C(α)-dependent NADPH oxidase activationEndothelin-A receptor blockade slows the progression of renal injury in experimental renovascular diseaseAngiotensin II-induced hypertension blunts thick ascending limb NO production by reducing NO synthase 3 expression and enhancing threonine 495 phosphorylation.Regulation of blood pressure and salt homeostasis by endothelin.Membrane-associated aquaporin-1 facilitates osmotically driven water flux across the basolateral membrane of the thick ascending limbBlood pressure, artery size, and artery compliance parallel bone size and strength in mice with differing ece1 expression.Nitric oxide reduces flow-induced superoxide production via cGMP-dependent protein kinase in thick ascending limbs.Angiotensin II decreases nitric oxide synthase 3 expression via nitric oxide and superoxide in the thick ascending limbExtracellular signal-regulated kinases 1/2 signaling pathways are not involved in endothelin regulation of mouse inner medullary collecting duct nitric oxide production.Physiology of endothelin and the kidney.Endothelin-1 inhibits thick ascending limb transport via Akt-stimulated nitric oxide production.Collecting duct-derived endothelin regulates arterial pressure and Na excretion via nitric oxide.Endothelin-1 stimulates NO production and inhibits cAMP accumulation in rat inner medullary collecting duct through independent pathways.
P2860
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P2860
Endothelin stimulates endothelial nitric oxide synthase expression in the thick ascending limb.
description
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name
Endothelin stimulates endothel ...... n in the thick ascending limb.
@en
Endothelin stimulates endothel ...... n in the thick ascending limb.
@nl
type
label
Endothelin stimulates endothel ...... n in the thick ascending limb.
@en
Endothelin stimulates endothel ...... n in the thick ascending limb.
@nl
prefLabel
Endothelin stimulates endothel ...... n in the thick ascending limb.
@en
Endothelin stimulates endothel ...... n in the thick ascending limb.
@nl
P2860
P1476
Endothelin stimulates endothel ...... n in the thick ascending limb.
@en
P2093
Jeffrey L Garvin
Marcela Herrera
P2860
P304
P356
10.1152/AJPRENAL.00413.2003
P577
2004-04-27T00:00:00Z