Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4.
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Prostaglandin E Receptor Subtype 4 Signaling in the Heart: Role in Ischemia/Reperfusion Injury and Cardiac HypertrophyThe contribution of prostaglandins versus prostacyclin in ventricular remodeling during heart failureE-type prostanoid receptor 4 (EP4) in disease and therapyThe Prostaglandin E2 Receptor EP4 Regulates Obesity-Related Inflammation and Insulin SensitivityAn Update of Microsomal Prostaglandin E Synthase-1 and PGE2 Receptors in Cardiovascular Health and DiseasesLY294002 inhibits glucocorticoid-induced COX-2 gene expression in cardiomyocytes through a phosphatidylinositol 3 kinase-independent mechanismPKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes.Gene expression profiling of dilated cardiomyopathy in older male EP4 knockout mice.Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanismsEmerging roles of PGE2 receptors in models of neurological disease.Prostacyclins have no direct inotropic effect on isolated atrial strips from the normal and pressure-overloaded human right heartPreserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2.Adiponectin actions in the cardiovascular system.Bioreducible polymers for therapeutic gene deliveryPAR1-dependent COX-2/PGE2 production contributes to cell proliferation via EP2 receptors in primary human cardiomyocytesLack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions.Understanding the role of prostaglandin E2 in regulating human platelet activity in health and diseaseDeletion of EP4 on bone marrow-derived cells enhances inflammation and angiotensin II-induced abdominal aortic aneurysm formation.Activation of prostaglandin E2-EP4 signaling reduces chemokine production in adipose tissue.Cytosolic phospholipase A(2)α protects against ischemia/reperfusion injury in the heart.Endothelium-mediated control of vascular tone: COX-1 and COX-2 products.Cardioprotection by adiponectin.Targeting adiponectin for cardioprotection.Adiponectin as an anti-inflammatory factor.N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1.Corticosteroids induce COX-2 expression in cardiomyocytes: role of glucocorticoid receptor and C/EBP-betaCardiomyocyte-targeted siRNA delivery by prostaglandin E(2)-Fas siRNA polyplexes formulated with reducible poly(amido amine) for preventing cardiomyocyte apoptosis.Staphylococcus aureus recognition by hematopoietic stem and progenitor cells via TLR2/MyD88/PGE2 stimulates granulopoiesis in wounds.Pharmacological activation of the prostaglandin E2 receptor EP4 improves cardiac function after myocardial ischaemia/reperfusion injuryBaicalin protects the myocardium from reperfusion-induced damage in isolated rat hearts via the antioxidant and paracrine effect.Potential of adiponectin as a cardioprotective agent.Prostaglandin E₂ promotes post-infarction cardiomyocyte replenishment by endogenous stem cellsProstaglandin E2 modulation of blood pressure homeostasis: studies in rodent models.Functional polymers of gene delivery for treatment of myocardial infarct.A sustained-release drug-delivery system of synthetic prostacyclin agonist, ONO-1301SR: a new reagent to enhance cardiac tissue salvage and/or regeneration in the damaged heart.The Role of Peroxisome Proliferator-Activated Receptor γ in Mediating Cardioprotection Against Ischemia/Reperfusion Injury.Prostaglandin E2 Reduces Cardiac Contractility via EP3 Receptor.Prostaglandin E2 in remote control of myocardial remodeling.Reduced cardiac remodeling and function in cardiac-specific EP4 receptor knockout mice with myocardial infarctionProstacyclin attenuates oxidative damage of myocytes by opening mitochondrial ATP-sensitive K+ channels via the EP3 receptor.
P2860
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P2860
Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Prostaglandin E2 protects the ...... via its receptor subtype EP4.
@en
Prostaglandin E2 protects the ...... via its receptor subtype EP4.
@nl
type
label
Prostaglandin E2 protects the ...... via its receptor subtype EP4.
@en
Prostaglandin E2 protects the ...... via its receptor subtype EP4.
@nl
prefLabel
Prostaglandin E2 protects the ...... via its receptor subtype EP4.
@en
Prostaglandin E2 protects the ...... via its receptor subtype EP4.
@nl
P2093
P1433
P1476
Prostaglandin E2 protects the ...... via its receptor subtype EP4.
@en
P2093
Akiyoshi Hara
Chun-Yang Xiao
Fumitaka Ushikubi
Hideji Karibe
Koh-ichi Yuhki
Koji Takayama
Osamu Takahata
Shuh Narumiya
Shuhko Kuriyama
Takanobu Taniguchi
P304
P356
10.1161/01.CIR.0000128046.54681.97
P407
P577
2004-05-03T00:00:00Z