The nucleoside derivative 5'-O-trityl-inosine (KIN59) suppresses thymidine phosphorylase-triggered angiogenesis via a noncompetitive mechanism of action.
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Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside AnaloguesThymidine Phosphorylase in Cancer; Enemy or Friend?Thymidine Phosphorylase Participates in Platelet Signaling and Promotes ThrombosisAntivascular and antitumor properties of the tubulin-binding chalcone TUB091Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plantsThe role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.Gene regulation and functional alterations induced by Kaposi's sarcoma-associated herpesvirus-encoded ORFK13/vFLIP in endothelial cells.Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implications for drug designThe Chick Embryo Chorioallantoic Membrane as an In Vivo Assay to Study Antiangiogenesis.Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues.Thymidine phosphorylase: A potential new target for treating cardiovascular disease.Direct Activation of NADPH Oxidase 2 by 2-Deoxyribose-1-Phosphate Triggers Nuclear Factor Kappa B-Dependent Angiogenesis.Thymidine phosphorylase is noncompetitively inhibited by 5'-O-trityl-inosine (KIN59) and related compounds.
P2860
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P2860
The nucleoside derivative 5'-O-trityl-inosine (KIN59) suppresses thymidine phosphorylase-triggered angiogenesis via a noncompetitive mechanism of action.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
The nucleoside derivative 5'-O ...... mpetitive mechanism of action.
@en
The nucleoside derivative 5'-O-trityl-inosine
@nl
type
label
The nucleoside derivative 5'-O ...... mpetitive mechanism of action.
@en
The nucleoside derivative 5'-O-trityl-inosine
@nl
prefLabel
The nucleoside derivative 5'-O ...... mpetitive mechanism of action.
@en
The nucleoside derivative 5'-O-trityl-inosine
@nl
P2860
P50
P356
P1476
The nucleoside derivative 5'-O ...... mpetitive mechanism of action.
@en
P2093
Ana-Isabel Hernández
María-Jesús Pérez-Pérez
P2860
P304
29598-29605
P356
10.1074/JBC.M402602200
P407
P577
2004-05-03T00:00:00Z