In vitro metabolism of etoposide (VP-16-213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins.

In vitro metabolism of etoposide (VP-16-213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins.

Item
http://www.wikidata.org/entity/Q44886202
Novel antitumor agents from higher plants.A review on plant-derived natural products and their analogs with anti-tumor activity.A phase I study on the reversal of multidrug resistance (MDR) in vivo: nifedipine plus etoposideButhionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulationOral treatment with etoposide in small cell lung cancer - dilemmas and solutions.Role of nitric oxide in the chemistry and anticancer activity of etoposide (VP-16,213).Nitric oxide inhibits topoisomerase II activity and induces resistance to topoisomerase II-poisons in human tumor cells.Effect of nitric oxide on the anticancer activity of the topoisomerase-active drugs etoposide and adriamycin in human melanoma cells.Interaction of anticancer drugs with hepatic monooxygenase enzymes.Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma.Biodegradability of the anticancer drug etoposide and identification of the transformation products.Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry.Cytochrome P-450- and peroxidase-dependent activation of procarbazine and iproniazid in mammalian cells.Tyrosinase-induced free radical formation from VP-16,213: relationship to cytotoxicity.Iron-dependent hydroxyl radical formation and DNA damage from a novel metabolite of the clinically active antitumor drug VP-16.Synergistic enhancement of topotecan-induced cell death by ascorbic acid in human breast MCF-7 tumor cells.
P2860

In vitro metabolism of etoposide (VP-16-213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins.

Item
http://www.wikidata.org/entity/Q44886202
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
In vitro metabolism of etoposi ...... diates to microsomal proteins.
@en
In vitro metabolism of etoposide
@nl
type
label
In vitro metabolism of etoposi ...... diates to microsomal proteins.
@en
In vitro metabolism of etoposide
@nl
prefLabel
In vitro metabolism of etoposi ...... diates to microsomal proteins.
@en
In vitro metabolism of etoposide
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
In vitro metabolism of etoposi ...... diates to microsomal proteins.
@en
P2093
P304
P31
P356
10.1016/0006-2952(87)90362-5
P407
P433
P478
P577
P698