Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclin-dependent kinase-2 activity.
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Statin use and breast cancer survival and risk: a systematic review and meta-analysisDifferential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sitesIn Perspective: Estrogen Therapy Proves to Safely and Effectively Reduce Total Mortality and Coronary Heart Disease in Recently Postmenopausal WomenDysregulation of the mevalonate pathway promotes transformationAssociation of lipid metabolism with ovarian cancerCholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma.Lipid phosphate phosphatase-2 activity regulates S-phase entry of the cell cycle in Rat2 fibroblasts.Statins and risk of cancer: a systematic review and metaanalysis.Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression.Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents.Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: Involvement of p53 and Fas receptor ligand complex2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent.Impact of cholesterol on disease progressionStatin use and the risk of colorectal adenoma: A meta-analysis.p53 regulates the mevalonate pathway in human glioblastoma multiforme.A comparison of cholesterol uptake and storage in inflammatory and noninflammatory breast cancer cells.Lipid mediators in membrane rafts are important determinants of human health and disease.Statins and colorectal cancer.Statin use in primary inflammatory breast cancer: a cohort study.Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics.Statins: do they have a potential role in cancer prevention and modifying cancer-related outcomes?The effect of statins on cancer cells--review.Exploitation of pleiotropic actions of statins by using tumour-targeted delivery systems.Inhibition of the mevalonate pathway augments the activity of pitavastatin against ovarian cancer cells.The interplay between cell signalling and the mevalonate pathway in cancer.Theasaponin E₁ as an effective ingredient for anti-angiogenesis and anti-obesity effects.Mevalonate pathway is a therapeutic target in esophageal squamous cell carcinoma.Monascus-fermented red mold rice exhibits cytotoxic effect and induces apoptosis on human breast cancer cells.Simvastatin impairs murine melanoma growth.Blockade of the RhoA-JNK-c-Jun-MMP2 cascade by atorvastatin reduces osteosarcoma cell invasion.The interplay between mutant p53 and the mevalonate pathway.Novel effects of statins in enhancing efficacy of chemotherapy in vitro in nasopharyngeal carcinoma.Exploring association between statin use and breast cancer risk: an updated meta-analysis.PPARα Antagonist AA452 Triggers Metabolic Reprogramming and Increases Sensitivity to Radiation Therapy in Human Glioblastoma Primary Cells.Effect of mevalonic acid on cholesterol synthesis in bovine intramuscular and subcutaneous adipocytes.Simvastatin inactivates beta1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells.Transcriptional profiles in liver from mice treated with hepatotumorigenic and nonhepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.DAMP, an acidotropic pH indicator, can be used as a tool to visualize non-esterified cholesterol in cells.Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling.
P2860
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P2860
Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclin-dependent kinase-2 activity.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Mevalonate promotes the growth ...... n-dependent kinase-2 activity.
@en
Mevalonate promotes the growth ...... n-dependent kinase-2 activity.
@nl
type
label
Mevalonate promotes the growth ...... n-dependent kinase-2 activity.
@en
Mevalonate promotes the growth ...... n-dependent kinase-2 activity.
@nl
prefLabel
Mevalonate promotes the growth ...... n-dependent kinase-2 activity.
@en
Mevalonate promotes the growth ...... n-dependent kinase-2 activity.
@nl
P2860
P356
P1476
Mevalonate promotes the growth ...... n-dependent kinase-2 activity.
@en
P2093
Michael C Archer
Robin E Duncan
P2860
P304
33079-33084
P356
10.1074/JBC.M400732200
P407
P577
2004-05-20T00:00:00Z