Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit. - Wikidata - wikimedia - TriplyDB

Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit.

Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit.

http://www.wikidata.org/entity/Q44920191

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Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches Calcium movements inside the sarcoplasmic reticulum of cardiac myocytes Pernicious attrition and inter-RyR2 CICR current control in cardiac muscle Alterations in T-tubule and dyad structure in heart disease: challenges and opportunities for computational analyses An integrated finite element simulation of cardiomyocyte function based on triphasic theory Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca2+ Release Patterns in Cardiomyocytes Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometries A multiscale computational model of spatially resolved calcium cycling in cardiac myocytes: from detailed cleft dynamics to the whole cell concentration profiles.Computational modeling of subcellular transport and signaling.Store-dependent deactivation: cooling the chain-reaction of myocardial calcium signaling.Nonlinear and Stochastic Dynamics in the Heart Finite Element Estimation of Protein-Ligand Association Rates with Post-Encounter Effects: Applications to Calcium binding in Troponin C and SERCA.Extraction of sub-microscopic Ca fluxes from blurred and noisy fluorescent indicator images with a detailed model fitting approach Superresolution modeling of calcium release in the heart The ryanodine receptor patchwork: knitting calcium spark dynamics.T-tubule disruption promotes calcium alternans in failing ventricular myocytes: mechanistic insights from computational modeling Long-Lasting Sparks: Multi-Metastability and Release Competition in the Calcium Release Unit Network Electron tomography of rabbit cardiomyocyte three-dimensional ultrastructure.Enzyme localization, crowding, and buffers collectively modulate diffusion-influenced signal transduction: Insights from continuum diffusion modeling.Ultrastructural Analysis of Self-Associated RyR2s A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation.Calcium Dynamics of Ex Vivo Long-Term Cultured CD8+ T Cells Are Regulated by Changes in Redox Metabolism.Hierarchical approaches for systems modeling in cardiac development.Influence of neighboring reactive particles on diffusion-limited reactions.Sensitivity of rabbit ventricular action potential and Ca²⁺ dynamics to small variations in membrane currents and ion diffusion coefficients.Molecular and subcellular-scale modeling of nucleotide diffusion in the cardiac myofilament lattice.Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.A model study of sequential enzyme reactions and electrostatic channeling.Decoding myocardial Ca²⁺ signals across multiple spatial scales: a role for sensitivity analysis.Regulation of RYR2 by sarcoplasmic reticulum Ca(2+).Modeling calcium regulation of contraction, energetics, signaling, and transcription in the cardiac myocyte.Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca2+ (mis)handling.Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention.Modeling Na+-Ca2+ exchange in the heart: Allosteric activation, spatial localization, sparks and excitation-contraction coupling.The emergence of subcellular pacemaker sites for calcium waves and oscillations.Evoked centripetal Ca(2+) mobilization in cardiac Purkinje cells: insight from a model of three Ca(2+) release regions.Ambiguous interactions between diastolic and SR Ca2+ in the regulation of cardiac Ca2+ release.Towards simulation of subcellular calcium dynamics at nanometre resolution The Subcellular Distribution of Ryanodine Receptors and L-Type Ca Channels Modulates Ca-Transient Properties and Spontaneous Ca-Release Events in Atrial Cardiomyocytes Calcium-Mediated Oscillation in Membrane Potentials and Atrial-Triggered Activity in Atrial Cells of Casq2 Mutation Mice

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Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit.

http://www.wikidata.org/entity/Q44920191

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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name

Modelling cardiac calcium spar ...... ion of a calcium release unit.

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Modelling cardiac calcium spar ...... ion of a calcium release unit.

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Modelling cardiac calcium spar ...... ion of a calcium release unit.

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Modelling cardiac calcium spar ...... ion of a calcium release unit.

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Modelling cardiac calcium spar ...... ion of a calcium release unit.

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Modelling cardiac calcium spar ...... ion of a calcium release unit.

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JPHYSIOL.2012.227926

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The Journal of Physiology

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Modelling cardiac calcium spar ...... ion of a calcium release unit.

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Andrew D McCulloch

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Andrew G Edwards

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Anushka P Michailova

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Johan Hake

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Masahiko Hoshijima

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Michael J Holst

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Peter M Kekenes-Huskey

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Zeyun Yu

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P2860

Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release

The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium.

Computational methods and challenges for large-scale circuit mapping

Computer visualization of three-dimensional image data using IMOD

Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle

Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum

Ca2+ stores regulate ryanodine receptor Ca2+ release channels via luminal and cytosolic Ca2+ sites

Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytes

Functional groups of ryanodine receptors in rat ventricular cells

Three-dimensional electron microscopy reveals new details of membrane systems for Ca2+ signaling in the heart.

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4403-4422

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10.1113/JPHYSIOL.2012.227926

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18

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J. Andrew McCammon

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2012-04-10T00:00:00Z

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223976888

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22495592

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