Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations. - Wikidata - wikimedia - TriplyDB

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations.

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations.

http://www.wikidata.org/entity/Q44938086

about

Crohn's disease: an immune deficiency state NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling Reduced Paneth cell alpha-defensins in ileal Crohn's disease Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)Function of Nod-like receptors in microbial recognition and host defense Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1beta generation Inflammasome in intestinal inflammation and cancer The inflammasome: an emerging therapeutic oncotarget for cancer prevention Recent advances in the genetics of autoimmune disease CARD15/NOD2 mutations in Crohn's disease Innate immune sensing of microbes by Nod proteins Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway Inflammatory bowel disease NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells.Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis.Induction of Nod1 and Nod2 intracellular pattern recognition receptors in murine osteoblasts following bacterial challenge.Etiopathogenesis of inflammatory bowel diseases Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum Deregulated inflammasome signaling in disease.Heterozygous nucleotide-binding oligomerization domain-2 mutations affect monocyte maturation in Crohn's disease.A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells Crohn's disease: innate immunodeficiency?The Nlrp3 inflammasome: contributions to intestinal homeostasis.NOD1 expression in the eye and functional contribution to IL-1beta-dependent ocular inflammation in mice.Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease.TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages.Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages The inflammasome adaptor ASC contributes to multiple innate immune processes in the resolution of otitis media.Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease.Interrelatedness between dysbiosis in the gut microbiota due to immunodeficiency and disease penetrance of colitis.Genome-wide expression profiling implicates a MAST3-regulated gene set in colonic mucosal inflammation of ulcerative colitis patients NOD1 in contrast to NOD2 functional polymorphism influence Chlamydia trachomatis infection and the risk of tubal factor infertility.Inflammasomes and Intestinal Tumorigenesis Inflammasomes in intestinal inflammation and cancer.Chronic stimulation of Nod2 mediates tolerance to bacterial products.TIR, CARD and PYRIN: three domains for an antimicrobial triad.Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.

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P2860

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations.

http://www.wikidata.org/entity/Q44938086

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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2004年學術文章

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name

Regulation of IL-8 and IL-1bet ...... ociated NOD2/CARD15 mutations.

@en

Regulation of IL-8 and IL-1bet ...... ociated NOD2/CARD15 mutations.

@nl

type

label

Regulation of IL-8 and IL-1bet ...... ociated NOD2/CARD15 mutations.

@en

Regulation of IL-8 and IL-1bet ...... ociated NOD2/CARD15 mutations.

@nl

prefLabel

Regulation of IL-8 and IL-1bet ...... ociated NOD2/CARD15 mutations.

@en

Regulation of IL-8 and IL-1bet ...... ociated NOD2/CARD15 mutations.

@nl

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Human Molecular Genetics

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Regulation of IL-8 and IL-1bet ...... ociated NOD2/CARD15 mutations.

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Christina Julian

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Clara Abraham

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Denise K Bonen

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Eric Swanson

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Jeremy Harris

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Judy H Cho

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Thomas Moran

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10.1093/HMG/DDH182

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