Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.
about
Fucofullerenes as tight ligands of RSL and LecB, two bacterial lectins.6-Azido hyacinthacine A2 gives a straightforward access to the first multivalent pyrrolizidine architectures.Therapeutic potential of carbohydrate-based polymeric and nanoparticle systems.Fullerene sugar balls: a new class of biologically active fullerene derivatives.The multivalent effect in glycosidase inhibition: a new, rapidly emerging topic in glycoscience.Multivalent inhibitors for carbohydrate-processing enzymes: beyond the "lock-and-key" concept.Synthesis of highly functionalized C60 fullerene derivatives and their applications in material and life sciences.Emerging trends in enzyme inhibition by multivalent nanoconstructs.Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases.Nanotechnology in Glycomics: Applications in Diagnostics, Therapy, Imaging, and Separation Processes.Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition.Synthesis of the first examples of iminosugar clusters based on cyclopeptoid coresDesign, synthesis and photochemical properties of the first examples of iminosugar clusters based on fluorescent cores.The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study.Multimeric xanthates as carbonic anhydrase inhibitors.Exploring carbonic anhydrase inhibition with multimeric coumarins displayed on a fullerene scaffold.Fullerene hexa-adduct scaffolding for the construction of giant molecules.Mechanistic Insight into Heptosyltransferase Inhibition by using Kdo Multivalent Glycoclusters.Pyruvate-Kinase-Coupled Glycosyltransferase Assays: Limitations, Struggles and Problem Resolution.Pillar[5]arene-Based Glycoclusters: Synthesis and Multivalent Binding to Pathogenic Bacterial Lectins.Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases.Multivalency To Inhibit and Discriminate Hexosaminidases.Cyclooctyne [60]fullerene hexakis adducts: a globular scaffold for copper-free click chemistry.Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier.Exploring the divalent effect in fucosidase inhibition with stereoisomeric pyrrolidine dimers.Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection
P2860
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P2860
Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Fullerene-sp2-iminosugar balls ...... inhibitory multivalent effect.
@en
Fullerene-sp2-iminosugar balls ...... inhibitory multivalent effect.
@nl
type
label
Fullerene-sp2-iminosugar balls ...... inhibitory multivalent effect.
@en
Fullerene-sp2-iminosugar balls ...... inhibitory multivalent effect.
@nl
prefLabel
Fullerene-sp2-iminosugar balls ...... inhibitory multivalent effect.
@en
Fullerene-sp2-iminosugar balls ...... inhibitory multivalent effect.
@nl
P2860
P356
P1476
Fullerene-sp2-iminosugar balls ...... inhibitory multivalent effect
@en
P2093
Jean-François Nierengarten
Rocío Rísquez-Cuadro
P2860
P304
16791-16803
P356
10.1002/CHEM.201303158
P407
P577
2013-10-22T00:00:00Z