NMR structure of the thromboxane A2 receptor ligand recognition pocket.
about
A strategy using NMR peptide structures of thromboxane A2 receptor as templates to construct ligand-recognition pocket of prostacyclin receptor.Invited review: GPCR structural characterization: Using fragments as building blocks to determine a complete structure.Solution NMR of signal peptidase, a membrane protein.Unraveling the structure and function of G protein-coupled receptors through NMR spectroscopy.Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation.An overview of recent developments in GPCR modelling: methods and validation.Cyclopentane-1,3-dione: a novel isostere for the carboxylic acid functional group. Application to the design of potent thromboxane (A2) receptor antagonists.A simple, quick, and high-yield preparation of the human thromboxane A2 receptor in full size for structural studies.Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist.Assembling NMR structures for the intracellular loops of the human thromboxane A2 receptor: implication of the G protein-coupling pocket.A profile of the residues in the second extracellular loop that are critical for ligand recognition of human prostacyclin receptor.Characterization of the prostaglandin H2 mimic: binding to the purified human thromboxane A2 receptor in solution.GPCR Conformations: Implications for Rational Drug Design.
P2860
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P2860
NMR structure of the thromboxane A2 receptor ligand recognition pocket.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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name
NMR structure of the thromboxane A2 receptor ligand recognition pocket.
@en
NMR structure of the thromboxane A2 receptor ligand recognition pocket.
@nl
type
label
NMR structure of the thromboxane A2 receptor ligand recognition pocket.
@en
NMR structure of the thromboxane A2 receptor ligand recognition pocket.
@nl
prefLabel
NMR structure of the thromboxane A2 receptor ligand recognition pocket.
@en
NMR structure of the thromboxane A2 receptor ligand recognition pocket.
@nl
P2093
P2860
P1433
P1476
NMR structure of the thromboxane A2 receptor ligand recognition pocket.
@en
P2093
Cheng-Huai Ruan
Ke-He Ruan
Lori A Jenkins
Shui-Ping So
P2860
P304
P356
10.1111/J.1432-1033.2004.04232.X
P407
P577
2004-07-01T00:00:00Z