Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration. - Wikidata - wikimedia - TriplyDB

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration.

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration.

http://www.wikidata.org/entity/Q44973262

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SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity Functions and regulation of circular dorsal ruffles P130Cas Src-binding and substrate domains have distinct roles in sustaining focal adhesion disassembly and promoting cell migration PTP1B inhibitor promotes endothelial cell motility by activating the DOCK180/Rac1 pathway.NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer P130Cas attenuates epidermal growth factor (EGF) receptor internalization by modulating EGF-triggered dynamin phosphorylation Abl silencing inhibits CAS-mediated process and constriction in resistance arteries p130Cas, Crk-associated substrate plays essential roles in liver development by regulating sinusoidal endothelial cell fenestration Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas The role of focal adhesion anchoring domains of CAS in mechanotransduction.A pre-metazoan origin of the CRK gene family and co-opted signaling network Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness Dynamics and mechanism of p130Cas localization to focal adhesions Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.Uncoupling Crk signal transduction by Pseudomonas exoenzyme T.N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.Integrin-mediated mechanotransduction pathway of low-intensity continuous ultrasound in human chondrocytes A FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly.Cullin 5 destabilizes Cas to inhibit Src-dependent cell transformation.Dissecting motility signaling through activation of specific Src-effector complexes p130Cas scaffolds the signalosome to direct adaptor-effector cross talk during Kaposi's sarcoma-associated herpesvirus trafficking in human microvascular dermal endothelial cells An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets.Extracellular matrix and its role in spermatogenesis Synthesis of functional signaling domains by combinatorial polymerization of phosphorylation motifs.LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer.Mesenchymal migration as a therapeutic target in glioblastoma.VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration Tyrosine Y189 in the substrate domain of the adhesion docking protein NEDD9 is conserved with p130Cas Y253 and regulates NEDD9-mediated migration and focal adhesion dynamics.Oligodendroglial p130Cas is a target of Fyn kinase involved in process formation, cell migration and survival.Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease.Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment p130CAS is required for netrin signaling and commissural axon guidance.Processive phosphorylation: mechanism and biological importance SRC points the way to biomarkers and chemotherapeutic targets.Src, p130Cas, and Mechanotransduction in Cancer Cells The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling Src binds cortactin through an SH2 domain cystine-mediated linkage.

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P2860

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration.

http://www.wikidata.org/entity/Q44973262

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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name

Subsets of the major tyrosine ...... ent to promote cell migration.

@en

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate

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type

label

Subsets of the major tyrosine ...... ent to promote cell migration.

@en

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate

@nl

prefLabel

Subsets of the major tyrosine ...... ent to promote cell migration.

@en

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate

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P1433

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P1433

Journal of Biological Chemistry

P1476

Subsets of the major tyrosine ...... ent to promote cell migration.

@en

P2093

Dawn M Kilkenny

http://www.w3.org/2001/XMLSchema#string

Jens Schneider-Mergener

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Nah-Young Shin

http://www.w3.org/2001/XMLSchema#string

Rebecca S Dise

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Steven K Hanks

http://www.w3.org/2001/XMLSchema#string

P2860

Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase.

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

A novel role for p120 catenin in E-cadherin function

The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

“Mosaic” Genes Highlight Forces of Genome Diversity and Adaptation

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38331-38337

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10.1074/JBC.M404675200

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37

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P478

279

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Marylyn D. Ritchie

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2004-07-06T00:00:00Z

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15247284

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phosphorylation