EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly.
about
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB functionProtein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASPA bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosisRecognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assemblyInsulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formationCommensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonizationAn extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their disseminationBioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretionVisualizing the Translocation and Localization of Bacterial Type III Effector Proteins by Using a Genetically Encoded Reporter System.Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspFUEnterohaemorrhagic Escherichia Coli Exploits a Tryptophan Switch to Hijack Host F-Actin AssemblyMechanism of actin filament nucleation by the bacterial effector VopLStructural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli.Type Three Secretion System in Attaching and Effacing PathogensThe QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC)Enteric Pathogens Exploit the Microbiota-generated Nutritional Environment of the GutInter-kingdom signaling: chemical language between bacteria and hostNck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector.Membrane-deforming proteins play distinct roles in actin pedestal biogenesis by enterohemorrhagic Escherichia coli.Physical mechanisms of signal integration by WASP family proteins.Hierarchical regulation of WASP/WAVE proteins.Cortactin recruitment by enterohemorrhagic Escherichia coli O157:H7 during infection in vitro and ex vivo.A novel two-component signaling system that activates transcription of an enterohemorrhagic Escherichia coli effector involved in remodeling of host actin.The Type Three Secretion System 2-Encoded Regulator EtrB Modulates Enterohemorrhagic Escherichia coli Virulence Gene Expression.The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways.Terminal reassortment drives the quantum evolution of type III effectors in bacterial pathogens.Genome evolution in major Escherichia coli O157:H7 lineagesGlobal transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal medium.Chlamydial entry involves TARP binding of guanine nucleotide exchange factors.Repetitive N-WASP-binding elements of the enterohemorrhagic Escherichia coli effector EspF(U) synergistically activate actin assembly.Shiga toxin in enterohemorrhagic E.coli: regulation and novel anti-virulence strategiesEnterohemorrhagic E. coli (EHEC) pathogenesis.Global analysis of posttranscriptional regulation by GlmY and GlmZ in enterohemorrhagic Escherichia coli O157:H7Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivoA comprehensive proteomic analysis of the type III secretome of Citrobacter rodentium.Enterohemorrhagic E. coli requires N-WASP for efficient type III translocation but not for EspFU-mediated actin pedestal formation.Evolution of genomic content in the stepwise emergence of Escherichia coli O157:H7.EspJ is a prophage-carried type III effector protein of attaching and effacing pathogens that modulates infection dynamics.Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3SepZ/EspZ is secreted and translocated into HeLa cells by the enteropathogenic Escherichia coli type III secretion system
P2860
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P2860
EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
EspFU is a translocated EHEC e ...... ck-independent actin assembly.
@en
EspFU is a translocated EHEC e ...... ck-independent actin assembly.
@nl
type
label
EspFU is a translocated EHEC e ...... ck-independent actin assembly.
@en
EspFU is a translocated EHEC e ...... ck-independent actin assembly.
@nl
prefLabel
EspFU is a translocated EHEC e ...... ck-independent actin assembly.
@en
EspFU is a translocated EHEC e ...... ck-independent actin assembly.
@nl
P2093
P1433
P1476
EspFU is a translocated EHEC e ...... ck-independent actin assembly.
@en
P2093
Douglas Robbins
John M Leong
Kenneth G Campellone
P304
P356
10.1016/J.DEVCEL.2004.07.004
P407
P577
2004-08-01T00:00:00Z