Identification and characterization of somatic steroid 5alpha-reductase (SRD5A2) mutations in human prostate cancer tissue.
about
Finasteride concentrations and prostate cancer risk: results from the Prostate Cancer Prevention Trial46,XY disorder of sexual development resulting from a novel monoallelic mutation (p.Ser31Phe) in the steroid 5α-reductase type-2 (SRD5A2) gene.Genomic biomarkers, androgen pathway and prostate cancer.Multiple steps determine the overall rate of the reduction of 5alpha-dihydrotestosterone catalyzed by human type 3 3alpha-hydroxysteroid dehydrogenase: implications for the elimination of androgens.The role of 5-alpha reductase inhibitors in prostate pathophysiology: Is there an additional advantage to inhibition of type 1 isoenzyme?Finasteride metabolism and pharmacogenetics: new approaches to personalized prevention of prostate cancer.Association of V89L SRD5A2 polymorphism with craving and serum leptin levels in male alcohol addicts.Genomic analysis of cancer tissue reveals that somatic mutations commonly occur in a specific motif.Effects of different ethanol-administration regimes on mRNA and protein levels of steroid 5α-reductase isozymes in prefrontal cortex of adolescent male rats.
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Identification and characterization of somatic steroid 5alpha-reductase (SRD5A2) mutations in human prostate cancer tissue.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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2004年學術文章
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2004年學術文章
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name
Identification and characteriz ...... human prostate cancer tissue.
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Identification and characterization of somatic steroid 5alpha-reductase
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type
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Identification and characteriz ...... human prostate cancer tissue.
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Identification and characterization of somatic steroid 5alpha-reductase
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Identification and characteriz ...... human prostate cancer tissue.
@en
Identification and characterization of somatic steroid 5alpha-reductase
@nl
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Identification and characteriz ...... human prostate cancer tissue.
@en
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Abebe Akalu
Nick Makridakis
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10.1038/SJ.ONC.1207922
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2004-09-01T00:00:00Z
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1017988678