PAR-1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia. - Wikidata - wikimedia - TriplyDB

PAR-1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia.

PAR-1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia.

http://www.wikidata.org/entity/Q45050935

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The Importance of Thrombin in Cerebral Injury and Disease Serine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behavior Learning and memory deficits in mice lacking protease activated receptor-1.Protease-activated receptor-1 activation by granzyme B causes neurotoxicity that is augmented by interleukin-1β Deficiency of PAR4 attenuates cerebral ischemia/reperfusion injury in mice Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.PAR1-activated astrocytes in the nucleus of the solitary tract stimulate adjacent neurons via NMDA receptors.Thrombin activity associated with neuronal damage during acute focal ischemia Stratification substantially reduces behavioral variability in the hypoxic-ischemic stroke model.Contribution of protease-activated receptor 1 in status epilepticus-induced epileptogenesis.Protease-activated receptor-1 modulates hippocampal memory formation and synaptic plasticity Baicalin protects against thrombin induced cell injury in SH-SY5Y cells Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function.A protease-activated receptor 1 antagonist protects against global cerebral ischemia/reperfusion injury after asphyxial cardiac arrest in rabbits.Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury Inhibition of Protease-Activated Receptor 1 Does not Affect Dendritic Homeostasis of Cultured Mouse Dentate Granule Cells.Role of protease-activated receptor-1 in brain injury after experimental global cerebral ischemia.PAR-1 antagonist SCH79797 ameliorates apoptosis following surgical brain injury through inhibition of ASK1-JNK in rats.Plasmin Activation of Glial Cells through Protease-Activated Receptor 1.Baicalin attenuates focal cerebral ischemic reperfusion injury by inhibition of protease-activated receptor-1 and apoptosis.Reduction of intracerebral hemorrhage by rivaroxaban after tPA thrombolysis is associated with downregulation of PAR-1 and PAR-2.

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PAR-1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia.

http://www.wikidata.org/entity/Q45050935

description

2004 nî lūn-bûn

@nan

2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

@zh-my

2004年学术文章

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2004年學術文章

@yue

2004年學術文章

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name

PAR-1 deficiency protects agai ...... ral cerebral hypoxia/ischemia.

@en

PAR-1 deficiency protects agai ...... ral cerebral hypoxia/ischemia.

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type

label

PAR-1 deficiency protects agai ...... ral cerebral hypoxia/ischemia.

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PAR-1 deficiency protects agai ...... ral cerebral hypoxia/ischemia.

@nl

prefLabel

PAR-1 deficiency protects agai ...... ral cerebral hypoxia/ischemia.

@en

PAR-1 deficiency protects agai ...... ral cerebral hypoxia/ischemia.

@nl

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Journal of Cerebral Blood Flow & Metabolism

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PAR-1 deficiency protects agai ...... ral cerebral hypoxia/ischemia.

@en

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Ellen E Olson

http://www.w3.org/2001/XMLSchema#string

Polina Lyuboslavsky

http://www.w3.org/2001/XMLSchema#string

Robert J McKeon

http://www.w3.org/2001/XMLSchema#string

Stephen F Traynelis

http://www.w3.org/2001/XMLSchema#string

P2860

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

Thrombin-receptor activation and thrombin-induced brain tolerance

Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways

Serine proteases and brain damage - is there a link?

Experimental stroke in the female diabetic, db/db, mouse.

Recommendations for standards regarding preclinical neuroprotective and restorative drug development.

The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective?

The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations.

The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia

The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death.

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