The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum.
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The evolution, metabolism and functions of the apicoplastUse of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparumChemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparumStructure of a bacterial pyridoxal 5'-phosphate synthase complexAnalysis of the vitamin B6 biosynthesis pathway in the human malaria parasite Plasmodium falciparumFosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathwaysNew Insight into Isoprenoids Biosynthesis Process and Future Prospects for Drug Designing in PlasmodiumIsoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasitesReconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparumIdentification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparumExpression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens.Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysisMetabolomics and malaria biologyVitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights.Isoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum.Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box.Squalestatin is an inhibitor of carotenoid biosynthesis in Plasmodium falciparum.Malaria parasites produce volatile mosquito attractantsHydroxybenzaldoximes Are D-GAP-Competitive Inhibitors of E. coli 1-Deoxy-D-Xylulose-5-Phosphate SynthaseSingle-target high-throughput transcription analyses reveal high levels of alternative splicing present in the FPPS/GGPPS from Plasmodium falciparum.Plasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target.Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum.Intraerythrocytic stages of Plasmodium falciparum biosynthesize menaquinoneVitamin and cofactor biosynthesis pathways in Plasmodium and other apicomplexan parasites.The non-mevalonate pathway of isoprenoid precursor biosynthesis.Vitamin B1 and B6 in the malaria parasite: requisite or dispensable?Discovery of a metabolic alternative to the classical mevalonate pathway.Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspDIsoprenoid biosynthesis in the erythrocytic stages of Plasmodium falciparum.Targeting the vitamin biosynthesis pathways for the treatment of malaria.Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum.Isoprenoid biosynthesis in Plasmodium falciparum.MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol: A substrate for IspE.Vitamin B1 de novo synthesis in the human malaria parasite Plasmodium falciparum depends on external provision of 4-amino-5-hydroxymethyl-2-methylpyrimidine.Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1Plasmodium falciparum uses vitamin E to avoid oxidative stress.A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.Sterol Composition and Biosynthetic Genes of Vitrella brassicaformis, a Recently Discovered Chromerid: Comparison to Chromera velia and Phylogenetic Relationship with Apicomplexan Parasites.Functional genetic analysis of the Plasmodium falciparum deoxyxylulose 5-phosphate reductoisomerase gene.
P2860
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P2860
The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
The methylerythritol phosphate ...... ages of Plasmodium falciparum.
@en
The methylerythritol phosphate ...... ages of Plasmodium falciparum.
@nl
type
label
The methylerythritol phosphate ...... ages of Plasmodium falciparum.
@en
The methylerythritol phosphate ...... ages of Plasmodium falciparum.
@nl
prefLabel
The methylerythritol phosphate ...... ages of Plasmodium falciparum.
@en
The methylerythritol phosphate ...... ages of Plasmodium falciparum.
@nl
P2093
P2860
P921
P356
P1476
The methylerythritol phosphate ...... ages of Plasmodium falciparum.
@en
P2093
Alejandro M Katzin
Emilia A Kimura
Emilio F Merino
Fabio C Gozzo
Fabio L D'Alexandri
Hassan Jomaa
Hernando A del Portillo
Igor C Almeida
Jochen Wiesner
Marcos N Eberlin
P2860
P304
51749-51759
P356
10.1074/JBC.M408360200
P407
P577
2004-09-27T00:00:00Z