Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.
about
Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanismTwo Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferasesUnderstanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT fromSulfolobus solfataricusCharacterization of a Cross-Linked Protein–Nucleic Acid Substrate Radical in the Reaction Catalyzed by RlmNFacile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analoguesStoichiometry of the redox neutral deamination and oxidative dehydrogenation reactions catalyzed by the radical SAM enzyme DesII.Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro.Mechanistic studies of the radical S-adenosylmethionine enzyme DesII with TDP-D-fucose.Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates.High-performance liquid chromatography separation of the (S,S)- and (R,S)-forms of S-adenosyl-L-methionineSynthesis and characterization of Se-adenosyl-L-selenohomocysteine selenoxide.Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8.Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation.Mechanistic Investigation of the Radical S-Adenosyl-L-methionine Enzyme DesII Using Fluorinated AnaloguesCysteine methylation controls radical generation in the Cfr radical AdoMet rRNA methyltransferaseA high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthasesCrystallographic snapshots of sulfur insertion by lipoyl synthase.Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.The mthA mutation conferring low-level resistance to streptomycin enhances antibiotic production in Bacillus subtilis by increasing the S-adenosylmethionine pool sizeSAM/SAH Analogs as Versatile Tools for SAM-Dependent Methyltransferases.Trifluoroselenomethionine: A New Unnatural Amino AcidInsights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects.AdoMet analog synthesis and utilization: current state of the art.Methyltransferase-Directed Labeling of Biomolecules and its Applications.Identification of an intermediate methyl carrier in the radical S-adenosylmethionine methylthiotransferases RimO and MiaB.Trans-sulfuration Pathway Seleno-amino Acids Are Mediators of Selenomethionine Toxicity in Saccharomyces cerevisiae.Large-scale, protection-free synthesis of Se-adenosyl-L-selenomethionine analogues and their application as cofactor surrogates of methyltransferasesFunctional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways.Evidence for a catalytically and kinetically competent enzyme-substrate cross-linked intermediate in catalysis by lipoyl synthaseFurther characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in the mechanism of catalysis.A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr.Characterization of RimO, a new member of the methylthiotransferase subclass of the radical SAM superfamilyBiochemical characterization of the HydE and HydG iron-only hydrogenase maturation enzymes from Thermatoga maritima.In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters.Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors.SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis.Automated One-pot Radiosynthesis of [11C]S-adenosyl Methionine.Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical S-adenosylmethionine methylase TsrM requires an unmodified N1 amine.Identification and Interrogation of the Herbicidin Biosynthetic Gene Cluster: First Insight into the Biosynthesis of a Rare Undecose Nucleoside Antibiotic.
P2860
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P2860
Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Insight into the polar reactiv ...... es of S-adenosyl-L-methionine.
@en
Insight into the polar reactiv ...... es of S-adenosyl-L-methionine.
@nl
type
label
Insight into the polar reactiv ...... es of S-adenosyl-L-methionine.
@en
Insight into the polar reactiv ...... es of S-adenosyl-L-methionine.
@nl
prefLabel
Insight into the polar reactiv ...... es of S-adenosyl-L-methionine.
@en
Insight into the polar reactiv ...... es of S-adenosyl-L-methionine.
@nl
P356
P1433
P1476
Insight into the polar reactiv ...... es of S-adenosyl-L-methionine.
@en
P2093
David F Iwig
Squire J Booker
P304
13496-13509
P356
10.1021/BI048693+
P407
P577
2004-10-01T00:00:00Z