Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

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Summary of information on human CYP enzymes: human P450 metabolism data.Drug bioactivation, covalent binding to target proteins and toxicity relevance.Metabolic studies on haloperidol and its tetrahydropyridinyl dehydration product (HPTP) in C57BL/6 mouse brain preparations.

P2860

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P2860

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

Item

http://www.wikidata.org/entity/Q45115174

description

1998 nî lūn-bûn

@nan

1998年の論文

@ja

1998年学术文章

@wuu

1998年学术文章

@zh

1998年学术文章

@zh-cn

1998年学术文章

@zh-hans

1998年学术文章

@zh-my

1998年学术文章

@zh-sg

1998年學術文章

@yue

1998年學術文章

@zh-hant

name

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

@en

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

@nl

type

Item

label

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

@en

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

@nl

prefLabel

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

@en

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

@nl

P1476

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

@en

P2093

Castagnoli N Jr

http://www.w3.org/2001/XMLSchema#string

Usuki E

http://www.w3.org/2001/XMLSchema#string

Van der Schyf CJ

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P2860

Pargyline prevents MPTP-induced parkinsonism in primates

Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects

Identification of potentially neurotoxic pyridinium metabolite in the urine of schizophrenic patients treated with haloperidol.

Metabolic studies on haloperidol and its tetrahydropyridine analog in C57BL/6 mice.

Oxidative polymorphism of debrisoquine in Parkinson's disease

Studies on the conversion of haloperidol and its tetrahydropyridine dehydration product to potentially neurotoxic pyridinium metabolites by human liver microsomes.

Studies on the metabolism of haloperidol (HP): the role of CYP3A in the production of the neurotoxic pyridinium metabolite HPP+ found in rat brain following ip administration of HP.

Two pyridinium metabolites of haloperidol are present in the brain of patients at post-mortem.

The MPTP-treated mouse as a model of parkinsonism: how good is it?

Membrane preconcentration-capillary electrophoresis-mass spectrometry in the analysis of biologically derived metabolites and biopolymers.

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809-826

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scholarly article

P356

10.3109/03602539808996331

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English

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P478

http://www.w3.org/2001/XMLSchema#string

P577

1998-11-01T00:00:00Z

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P698

9844810

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Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

about

P2860

P2860

Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698