Rb1 haploinsufficiency promotes telomere attrition and radiation-induced genomic instability.
about
A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice.Direct involvement of retinoblastoma family proteins in DNA repair by non-homologous end-joining.Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited to copy number changes.Cytogenetic alterations and their molecular genetic correlates in head and neck squamous cell carcinoma: a next generation window to the biology of disease.IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination.Conditional haploinsufficiency of the retinoblastoma tumor suppressor gene.The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression.Tumors of the upper aerodigestive tract
P2860
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P2860
Rb1 haploinsufficiency promotes telomere attrition and radiation-induced genomic instability.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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name
Rb1 haploinsufficiency promote ...... n-induced genomic instability.
@en
Rb1 haploinsufficiency promote ...... n-induced genomic instability.
@nl
type
label
Rb1 haploinsufficiency promote ...... n-induced genomic instability.
@en
Rb1 haploinsufficiency promote ...... n-induced genomic instability.
@nl
prefLabel
Rb1 haploinsufficiency promote ...... n-induced genomic instability.
@en
Rb1 haploinsufficiency promote ...... n-induced genomic instability.
@nl
P50
P1433
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Rb1 haploinsufficiency promote ...... n-induced genomic instability.
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P2093
Bahar Sanli-Bonazzi
Olena Klymenko
P304
P356
10.1158/0008-5472.CAN-12-3117
P407
P577
2013-05-16T00:00:00Z