Dimeric galectin-1 binds with high affinity to alpha2,3-sialylated and non-sialylated terminal N-acetyllactosamine units on surface-bound extended glycans.
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Regulation of renal outer medullary potassium channel and renal K(+) excretion by KlothoHuman galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cellsGalectins and their ligands: negative regulators of anti-tumor immunityGalectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular DystrophyExpression of galectin-1, a new component of slit diaphragm, is altered in minimal change nephrotic syndromeST6Gal-I regulates macrophage apoptosis via α2-6 sialylation of the TNFR1 death receptorStructural characterisation of neutrophil glycans by ultra sensitive mass spectrometric glycomics methodologyNovel fluorescent glycan microarray strategy reveals ligands for galectins.N- and O-glycans modulate galectin-1 binding, CD45 signaling, and T cell death.Differential expression of immunomodulatory galectin-1 in peripheral leukocytes and adult tissues and its cytosolic organization in striated muscle.Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation.Galatrox is a C-type lectin in Bothrops atrox snake venom that selectively binds LacNAc-terminated glycans and can induce acute inflammation.Emerging role of alpha2,6-sialic acid as a negative regulator of galectin binding and function.The anti-angiogenic peptide anginex greatly enhances galectin-1 binding affinity for glycoproteins.Molecular basis of Klotho: from gene to function in agingGalectin-1 regulates tissue exit of specific dendritic cell populations.Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc) oligomers and N,N-diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment.When galectins recognize glycans: from biochemistry to physiology and back againGalectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens.Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1Engineering galectin-glycan interactions for immunotherapy and immunomodulationCD45 glycosylation controls T-cell life and death.Galectin-1 signaling in leukocytes requires expression of complex-type N-glycans.Klotho: a novel regulator of calcium and phosphorus homeostasis.Identification of galectins as novel regulators of platelet signaling and function.Galectin-1 and -9 in angiogenesis: a sweet couple.Evolving mechanistic insights into galectin functions.Sialylation of beta1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis.Galectin Binding to Neo-Glycoproteins: LacDiNAc Conjugated BSA as Ligand for Human Galectin-3.Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells.Examination of whole cell galectin binding by solid phase and flow cytometric analysis.The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells.Galectin-1 inhibitors and their potential therapeutic applications: a patent review.A key role for galectin-1 in sprouting angiogenesis revealed by novel rationally designed antibodies.Key regulators of galectin-glycan interactions.Dimeric Galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the C-terminal domain.Possible role of sialylation of retinal protein glycans in the regulation of electroretinogram response in mice.Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3.Loss of effector function of human cytolytic T lymphocytes is accompanied by major alterations in N- and O-glycosylation.
P2860
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P2860
Dimeric galectin-1 binds with high affinity to alpha2,3-sialylated and non-sialylated terminal N-acetyllactosamine units on surface-bound extended glycans.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Dimeric galectin-1 binds with ...... urface-bound extended glycans.
@en
Dimeric galectin-1 binds with ...... urface-bound extended glycans.
@nl
type
label
Dimeric galectin-1 binds with ...... urface-bound extended glycans.
@en
Dimeric galectin-1 binds with ...... urface-bound extended glycans.
@nl
prefLabel
Dimeric galectin-1 binds with ...... urface-bound extended glycans.
@en
Dimeric galectin-1 binds with ...... urface-bound extended glycans.
@nl
P2093
P2860
P356
P1476
Dimeric galectin-1 binds with ...... surface-bound extended glycans
@en
P2093
Anne Leppänen
Richard D Cummings
Sean Stowell
P2860
P304
P356
10.1074/JBC.M412019200
P407
P50
P577
2004-11-19T00:00:00Z