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The role of modifications in codon discrimination by tRNA(Lys)UUU.

The role of modifications in codon discrimination by tRNA(Lys)UUU.

http://www.wikidata.org/entity/Q45159086

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Structural and evolutionary classification of G/U wobble basepairs in the ribosome Nucleoside modifications in the regulation of gene expression: focus on tRNA From Prebiotics to Probiotics: The Evolution and Functions of tRNA Modifications Exploiting tRNAs to Boost Virulence Structure of transfer RNAs: similarity and variability Biosynthesis and functions of sulfur modifications in tRNA Modification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxes Diversity of the biosynthesis pathway for threonylcarbamoyladenosine (t(6)A), a universal modification of tRNA Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U.G wobble pairing during decoding The structure of the human tRNALys3 anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairs Snapshots of Dynamics in Synthesizing N 6 -Isopentenyladenosine at the tRNA Anticodon Structural aspects of messenger RNA reading frame maintenance by the ribosome How mutations in tRNA distant from the anticodon affect the fidelity of decoding Crystal structure of Sulfolobus tokodaii Sua5 complexed with L-threonine and AMPPNP Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli Human tRNALys3UUU Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto–Enol Tautomerism The structural basis for specific decoding of AUA by isoleucine tRNA on the ribosome The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase The O-carbamoyltransferase TobZ catalyzes an ancient enzymatic reaction Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system Solution Nuclear Magnetic Resonance Analyses of the Anticodon Arms of Proteinogenic and Nonproteinogenic tRNA Gly Expanded use of sense codons is regulated by modified cytidines in tRNA The central role of protein S12 in organizing the structure of the decoding site of the ribosome Structure ofSaccharomyces cerevisiaemitochondrial Qri7 in complex with AMP Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesis The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA.The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A.Functional assignment of KEOPS/EKC complex subunits in the biosynthesis of the universal t6A tRNA modification.A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast The Sua5 protein is essential for normal translational regulation in yeast.Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop.A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α Discovery of the β-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1 Biosynthesis of threonylcarbamoyl adenosine (t6A), a universal tRNA nucleoside The crystal structure and small-angle X-ray analysis of CsdL/TcdA reveal a new tRNA binding motif in the MoeB/E1 superfamily Synthesis, base pairing and structure studies of geranylated RNA tRNA biology charges to the front Identification of Plasmodium falciparum apicoplast-targeted tRNA-guanine transglycosylase and its potential inhibitors using comparative genomics, molecular modelling, docking and simulation studies

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The role of modifications in codon discrimination by tRNA(Lys)UUU.

http://www.wikidata.org/entity/Q45159086

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2004 nî lūn-bûn

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2004年の論文

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The role of modifications in codon discrimination by tRNA

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The role of modifications in codon discrimination by tRNA(Lys)UUU.

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The role of modifications in codon discrimination by tRNA

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The role of modifications in codon discrimination by tRNA(Lys)UUU.

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The role of modifications in codon discrimination by tRNA

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The role of modifications in codon discrimination by tRNA(Lys)UUU.

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Nature Structural & Molecular Biology

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The role of modifications in codon discrimination by tRNA(Lys)UUU.

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Andrzej Malkiewicz

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Frank V Murphy

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Paul F Agris

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P2860

Improvement of reading frame maintenance is a common function for several tRNA modifications.

Purine bases at position 37 of tRNA stabilize codon-anticodon interaction in the ribosomal A site by stacking and Mg2+-dependent interactions.

Total chemical synthesis of a 77-nucleotide-long RNA sequence having methionine-acceptance activity

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Processing of X-ray diffraction data collected in oscillation mode

Hypermodified nucleosides in the anticodon of tRNALys stabilize a canonical U-turn structure

Functional anticodon architecture of human tRNALys3 includes disruption of intraloop hydrogen bonding by the naturally occurring amino acid modification, t6A

The crystal structure of HIV reverse-transcription primer tRNA(Lys,3) shows a canonical anticodon loop

Recognition of cognate transfer RNA by the 30S ribosomal subunit

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12

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11

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Venkatraman Ramakrishnan

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2004-11-21T00:00:00Z

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