A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
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Cloning and recombinant expression of rat and human kynureninaseDifferent kynurenine pathway enzymes limit quinolinic acid formation by various human cell typesCloning and functional expression of human kynurenine 3-monooxygenaseThe physiological action of picolinic Acid in the human brainCytokine effects on the basal ganglia and dopamine function: the subcortical source of inflammatory malaiseInhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferasesIsolation and expression of a cDNA clone encoding human kynureninaseHuman microglia convert l-tryptophan into the neurotoxin quinolinic acidThe pharmacokinetic-pharmacodynamic model of azithromycin for lipopolysaccharide-induced depressive-like behavior in miceNeurotoxic and neuroprotective metabolites of kynurenine in patients with renal cell carcinoma treated with interferon-alpha: course and relationship with psychiatric status.CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depressionEffects of antidepressants and cyclooxygenase-2 inhibitor on cytokines and kynurenines in stimulated in vitro blood culture from depressed patients.Kynurenines: from the perspective of major psychiatric disorders.Microglia in HIV-associated neurological diseases.Study of the brain serotonergic system with labeled alpha-methyl-L-tryptophan.Inflammation, depression and dementia: are they connected?Etiological classification of depression based on the enzymes of tryptophan metabolism.Changes in the immune system in depression and dementia: causal or coincidental effects?Tyrosine metabolism during interferon-alpha administration: association with fatigue and CSF dopamine concentrationsInflammation and depression: is there a causal connection with dementia?HPA and immune axes in stress: involvement of the serotonergic system.Brain regional α-[11C]methyl-L-tryptophan trapping in medication-free patients with obsessive-compulsive disorder.Microglia/macrophage-derived inflammatory mediators galectin-3 and quinolinic acid are elevated in cerebrospinal fluid from newborn infants after birth asphyxiaAttenuation of antigenic immunogenicity by kynurenine, a novel suppressive adjuvant.Tryptophan-kynurenine pathway is dysregulated in inflammation, and immune activation.Gene regulation and functional alterations induced by Kaposi's sarcoma-associated herpesvirus-encoded ORFK13/vFLIP in endothelial cells.Kynurenine pathway dysfunction in the pathophysiology and treatment of depression: Evidences from animal and human studiesThe psychoneuroimmunology of depression.Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease.Kynurenines, neurodegeneration and Alzheimer's disease.The role of the kynurenine metabolism in major depression.Aryl hydrocarbon receptor and kynurenine: recent advances in autoimmune disease researchCentral Nervous System Infection with Borna Disease Virus Causes Kynurenine Pathway Dysregulation and Neurotoxic Quinolinic Acid ProductionThe role of macrophage polarization on bipolar disorder: Identifying new therapeutic targets.Influence of miR-30b regulating humoral immune response by genetic difference.Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway.Excitotoxicity of quinolinic acid: modulation by endogenous antagonists.The activation of the kynurenine pathway in a rat model with renovascular hypertension.Species and cell types difference in tryptophan metabolism.Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain.
P2860
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P2860
A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
A mechanism of quinolinic acid ...... -chloro-3-hydroxyanthranilate.
@en
A mechanism of quinolinic acid ...... -chloro-3-hydroxyanthranilate.
@nl
type
label
A mechanism of quinolinic acid ...... -chloro-3-hydroxyanthranilate.
@en
A mechanism of quinolinic acid ...... -chloro-3-hydroxyanthranilate.
@nl
prefLabel
A mechanism of quinolinic acid ...... -chloro-3-hydroxyanthranilate.
@en
A mechanism of quinolinic acid ...... -chloro-3-hydroxyanthranilate.
@nl
P2093
P356
P1433
P1476
A mechanism of quinolinic acid ...... -chloro-3-hydroxyanthranilate.
@en
P2093
P304
P356
10.1093/BRAIN/116.6.1425
P407
P478
116 ( Pt 6)
P577
1993-12-01T00:00:00Z