Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.
about
TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKLThe Yersinia enterocolitica effector YopP inhibits host cell signalling by inactivating the protein kinase TAK1 in the IL-1 signalling pathwayProtein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathwayPPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activationDirect activation of protein kinases by unanchored polyubiquitin chainsVaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1PKC beta regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathwaysTGF-β signaling via TAK1 pathway: role in kidney fibrosisCrystal structure of the p38α MAP kinase in complex with a docking peptide from TAB1Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular processTAB-1 modulates intracellular localization of p38 MAP kinase and downstream signalingStress-stimulated mitogen-activated protein kinases control the stability and activity of the Cdt1 DNA replication licensing factorTransforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway.Protein phosphatase 2A is a negative regulator of transforming growth factor-beta1-induced TAK1 activation in mesangial cellsFrequent downregulation of BTB and CNC homology 2 expression in Epstein-Barr virus-positive diffuse large B-cell lymphoma.HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1.TTRAP is a novel component of the non-canonical TRAF6-TAK1 TGF-β signaling pathwayTGF-β-activated kinase 1 is crucial in podocyte differentiation and glomerular capillary formation.Transforming growth factor (TGF)-β-activated kinase 1 (TAK1) activation requires phosphorylation of serine 412 by protein kinase A catalytic subunit α (PKACα) and X-linked protein kinase (PRKX).Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1.TRAF6 promotes myogenic differentiation via the TAK1/p38 mitogen-activated protein kinase and Akt pathways.Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling.Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene, is involved in positive regulation of TNF induced NF-κB pathway.A novel rabbit immunospot array assay on a chip allows for the rapid generation of rabbit monoclonal antibodies with high affinityTherapeutic targets for treating fibrotic kidney diseasesActivated macrophage survival is coordinated by TAK1 binding proteinsTAK1-TAB2 signaling contributes to bone destruction by breast carcinoma cellsTargeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer.FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization.Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen speciesPolyubiquitination of Transforming Growth Factor β-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4-mediated JNK and p38 MAPK Activation.TGFβ-activated Kinase 1 (TAK1) Inhibition by 5Z-7-Oxozeaenol Attenuates Early Brain Injury after Experimental Subarachnoid HemorrhageSerine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signalingTAK1 modulates satellite stem cell homeostasis and skeletal muscle repairUbiquitin, TAK1 and IKK: is there a connection?TGF-β-activated kinase-1: New insights into the mechanism of TGF-β signaling and kidney disease.Sequence-specific activation of TAK1-D by short double-stranded RNAs induces apoptosis in NCI-H460 cellsA comprehensive map of the toll-like receptor signaling network.The dual-specificity phosphatase DUSP14 negatively regulates tumor necrosis factor- and interleukin-1-induced nuclear factor-κB activation by dephosphorylating the protein kinase TAK1
P2860
Q21092160-6FFCC010-7A1D-4123-BE1E-D141A7F74750Q24297208-1D03BC40-B0B3-494A-926B-CDDADAB52A52Q24310895-37F3B6BA-51F3-4260-AF6F-5FCB66DF010AQ24324459-5814DF2F-4628-489B-AB6A-4ED128EB2B9FQ24324679-6F9E946A-1854-48AF-AFE4-C906C332E96CQ24337845-8204D81C-76DE-48BE-8523-20B8409CEE59Q24646391-4E773BEE-9A15-4329-82D0-4A245D4F4DF6Q24676236-2EB00306-77DE-4BB1-A912-9C075EB47BB6Q26824337-6E444ADC-7859-4AFC-BB6B-25B9976C22C9Q27684727-20828931-BAC7-4A8A-890A-7B0EA5DBD580Q28117206-9A69497F-D272-46A9-9789-1877598F79CEQ28581551-AF4C359F-53CC-43F9-85C5-BA17F258EBBDQ30427155-D4BC106E-E3FD-4FF3-9B9C-FA6A723ABBADQ30433440-A0973001-E5E6-40C8-B7CC-00FE649D8556Q30439818-95FA1BAD-E82C-485B-A4C6-10175B6892C7Q33738811-FC1F91E2-454A-46F4-AB77-5743C965D985Q33756614-1DE8450E-6C56-4373-AD2F-B3EC1E867E41Q34043345-94CCC051-531E-42FA-9AC6-AB02B0379CAAQ34103389-D9D04732-B8F8-4E48-8C2E-72B6415FFA1FQ34107219-BE7AE6FF-5C39-4703-B753-1844B2FA90A2Q34117399-4F170B7B-85AA-4798-9FF3-845E345E8BD3Q34229995-2FF5F637-4CB8-4C6B-8B10-DCB9B4B8CD34Q34365776-B0D541D0-298B-4B1D-BC6A-4213F1A31552Q34477410-3E0263BB-9110-4259-8340-F827C3836B24Q34540651-98CA471A-CA1C-42B8-9140-5AB70F74001DQ35079607-9E6C1B51-58B8-4752-89BB-A780A2A635A2Q35149590-69CDF446-6ED6-4A60-91F1-1268AA1B5B71Q35169027-74C7B197-5932-4730-8F4A-2F1480054BF2Q35176207-50E4C30F-DCFC-4F33-BAA1-2C06BD99C64EQ35622770-3661108B-11DF-4F80-ACAC-F19C4616327BQ35807430-9427D974-075F-40BC-A964-F8171BB2F608Q35865778-66006A9C-6D35-4507-8854-CB1EF149E12BQ35925884-D707C834-B115-4065-AF7D-A4040CCF8143Q36140258-AA882C0B-4B2B-42C7-9A1E-E4B7DCBDC053Q36379442-FD207378-EA24-40B3-AA27-69BA8BF36122Q36399446-C84E0127-77A9-4E64-A6C8-89727616EB5FQ36468657-B554D478-B943-4B51-9D9E-9FA5F2DC914DQ36470294-BF11E163-5628-46D2-A776-EF3195E3BACDQ36494115-2B5B2E1D-E5F2-4AC9-A500-60BC46EB7FDBQ36526359-775A3EBD-9C15-451F-9190-F1B4CEFF5B88
P2860
Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Critical roles of threonine 18 ...... binding protein TAB1 and TAB2.
@en
Critical roles of threonine 18 ...... factor-beta-activated kinase 1
@nl
type
label
Critical roles of threonine 18 ...... binding protein TAB1 and TAB2.
@en
Critical roles of threonine 18 ...... factor-beta-activated kinase 1
@nl
prefLabel
Critical roles of threonine 18 ...... binding protein TAB1 and TAB2.
@en
Critical roles of threonine 18 ...... factor-beta-activated kinase 1
@nl
P2093
P2860
P356
P1476
Critical roles of threonine 18 ...... binding protein TAB1 and TAB2.
@en
P2093
Ikuo Saiki
Noritaka Kawasaki
Pattama Singhirunnusorn
Shunsuke Suzuki
P2860
P304
P356
10.1074/JBC.M407537200
P407
P577
2004-12-07T00:00:00Z