Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
about
A balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytesTelomerase Activation in Hematological MalignanciesTumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell LeukemiaIncreased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia.HTLV-1 positive and negative T cells cloned from infected individuals display telomerase and telomere genes deregulation that predominate in activated but untransformed CD4+ T cells.Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence.Multiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia.The importance of the telomere and telomerase system in hematological malignancies.The role of telomere biology in bone marrow failure and other disordersTreatment of adult T-cell leukemia/lymphoma: past, present, and future.Regulation of telomerase and telomeres: human tumor viruses take control.Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected SubjectsTelomere/telomerase interplay in virus-driven and virus-independent lymphomagenesis: pathogenic and clinical implications.Telomere dysfunction and its role in haematological cancer.Association between telomere length and survival in cancer patients: a meta-analysis and review of literature.A common variant near TERC and telomere length are associated with susceptibility to childhood acute lymphoblastic leukemia in Chinese.Antiproliferative effect of rapamycin on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomerase inhibition.HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT).Antagonistic effect of the tumor suppressor Menin and the HBZ protein of HTLV-1 on telomerase activity.Inhibition of the hTERT promoter by the proto-oncogenic protein TAL1.
P2860
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P2860
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
@en
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
@nl
type
label
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
@en
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
@nl
prefLabel
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
@en
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
@nl
P2093
P2860
P1433
P1476
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
@en
P2093
Akihiko Okayama
Hidenori Sasaki
Hirohito Tsubouchi
Hitoshi Matsuoka
Kiyoshi Yamashita
Koichi Maeda
Muneou Suzuki
Takanori Toyama
Toshio Nakanishi
P2860
P304
P356
10.1080/10428190400018349
P577
2005-03-01T00:00:00Z