Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function.
about
Mendelian randomization studies: a review of the approaches used and the quality of reportingMendelian Randomization as an Approach to Assess Causality Using Observational Data.ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approachesSerum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studiesImpact of comorbidities on gout and hyperuricaemia: an update on prevalence and treatment optionsRenal clearance of uric acid is linked to insulin resistance and lower excretion of sodium in gout patients.Mendelian randomization provides no evidence for a causal role of serum urate in increasing serum triglyceride levels.An update on the genetic architecture of hyperuricemia and goutSerum urate gene associations with incident gout, measured in the Framingham Heart Study, are modified by renal disease and not by body mass index.Type 2 Diabetes, Diabetes Genetic Score and Risk of Decreased Renal Function and Albuminuria: A Mendelian Randomization Study.Pharmacogenetic considerations in the treatment of gout.Asymptomatic Hyperuricemia Without Comorbidities Predicts Cardiometabolic Diseases: Five-Year Japanese Cohort Study.Time to target uric acid to retard CKD progression.Insight into rheumatological cause and effect through the use of Mendelian randomization.Variability in HbA1c, blood pressure, lipid parameters and serum uric acid, and risk of development of chronic kidney disease in type 2 diabetes.No causal effect of serum urate on bone-related outcomes among a population of postmenopausal women and elderly men of Chinese Han ethnicity--a Mendelian randomization study.Opposing effects of sodium intake on uric acid and blood pressure and their causal implication.Mendelian randomization analysis to examine for a causal effect of urate on bone mineral density.DNA hypomethylation of a transcription factor binding site within the promoter of a gout risk gene NRBP1 upregulates its expression by inhibition of TFAP2A bindingEarly-onset metabolic syndrome in mice lacking the intestinal uric acid transporter SLC2A9.Elevated serum urate is a potential factor in reduction of total bilirubin: a Mendelian randomization study.Uric acid and incident chronic kidney disease in dyslipidemic individuals.Uric acid and cardiovascular risk: What genes can say.Cardiac and renal protective effects of urate-lowering therapy.MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank.Causal or Noncausal Relationship of Uric Acid With Diabetes.Physiology of Hyperuricemia and Urate-Lowering Treatments.Uric Acid and Decline in Renal Function-Partners in Crime
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P2860
Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Mendelian randomization analys ...... with improved renal function.
@en
Mendelian randomization analys ...... with improved renal function.
@nl
type
label
Mendelian randomization analys ...... with improved renal function.
@en
Mendelian randomization analys ...... with improved renal function.
@nl
prefLabel
Mendelian randomization analys ...... with improved renal function.
@en
Mendelian randomization analys ...... with improved renal function.
@nl
P2860
P50
P356
P1433
P1476
Mendelian randomization analys ...... with improved renal function.
@en
P2093
Janak de Zoysa
Kim Hughes
P2860
P2888
P304
P356
10.1038/KI.2013.353
P407
P577
2013-09-18T00:00:00Z
P5875
P6179
1052942929