A phase I and pharmacokinetic study of short infusions of UCN-01 in patients with refractory solid tumors.

A phase I and pharmacokinetic study of short infusions of UCN-01 in patients with refractory solid tumors.

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http://www.wikidata.org/entity/Q45258277
CHK1 inhibitors in combination chemotherapy: thinking beyond the cell cycleTrial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapyThe effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivityA Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignanciesHistone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cellsA phase I trial of UCN-01 and prednisone in patients with refractory solid tumors and lymphomas.Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells.Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death.A phase II study of cell cycle inhibitor UCN-01 in patients with metastatic melanoma: a California Cancer Consortium trial.Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activationPharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trialGSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers.Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumorsNew combination therapies with cell-cycle agentsSuppression of antifolate resistance by targeting the myosin Va trafficking pathway in melanoma.Protein kinase C: an attractive target for cancer therapy.ATR/CHK1 inhibitors and cancer therapy.
P2860

A phase I and pharmacokinetic study of short infusions of UCN-01 in patients with refractory solid tumors.

Item
http://www.wikidata.org/entity/Q45258277
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
A phase I and pharmacokinetic ...... with refractory solid tumors.
@en
A phase I and pharmacokinetic ...... with refractory solid tumors.
@nl
type
label
A phase I and pharmacokinetic ...... with refractory solid tumors.
@en
A phase I and pharmacokinetic ...... with refractory solid tumors.
@nl
prefLabel
A phase I and pharmacokinetic ...... with refractory solid tumors.
@en
A phase I and pharmacokinetic ...... with refractory solid tumors.
@nl
P1433
P1476
P2093
P304
P31
P407
P433
P478
P577
P698
P1433
P1476
A phase I and pharmacokinetic ...... with refractory solid tumors.
@en
P2093
P304
P31
P407
P433
P478
P577
P698