Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis.
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Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-makingA critical analysis of the biological impacts of plasticizers on wildlifeWhat should it take to describe a substance or product as 'sperm-safe'In utero exposure to di-(2-ethylhexyl) phthalate induces testicular effects in neonatal rats that are antagonized by genistein cotreatmentEffect of chemical mutagens and carcinogens on gene expression profiles in human TK6 cellsMetabolomics in the assessment of chemical-induced reproductive and developmental outcomes using non-invasive biological fluids: application to the study of butylbenzyl phthalateIdentification of Drosophila-based endpoints for the assessment and understanding of xenobiotic-mediated male reproductive adversitiesRodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dustSpecies-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathwaysTargeting testis-specific proteins to inhibit spermatogenesis: lesson from endocrine disrupting chemicals.Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis.Dietary exposure of Nigerians to mutagens and estrogen-like chemicals.Personal care products and endocrine disruption: A critical review of the literature.A critical assessment of the endocrine susceptibility of the human testis to phthalates from fetal life to adulthood.Cellular and molecular effect of MEHP Involving LXRα in human fetal testis and ovary.Toxicogenomic Screening of Replacements for Di(2-Ethylhexyl) Phthalate (DEHP) Using the Immortalized TM4 Sertoli Cell LineIn utero exposure to butyl benzyl phthalate induces modifications in the morphology and the gene expression profile of the mammary gland: an experimental study in rats.Dipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates.Local signalling environments and human male infertility: what we can learn from mouse models.In utero exposure to the antiandrogen di-(2-ethylhexyl) phthalate decreases adrenal aldosterone production in the adult rat.Man is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetusDi (2-ethylhexyl) phthalate inhibits growth of mouse ovarian antral follicles through an oxidative stress pathwayTesticular connexin 43, a precocious molecular target for the effect of environmental toxicants on male fertilityDose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in RatsOf mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent.Possible impact of phthalates on infant reproductive health.Proposed mode of action for in utero effects of some phthalate esters on the developing male reproductive tract.Phthalate diesters and their metabolites in human breast milk, blood or serum, and urine as biomarkers of exposure in vulnerable populations.Dose-dependent effects on cell proliferation, seminiferous tubules, and male germ cells in the fetal rat testis following exposure to di(n-butyl) phthalateThe steroidogenic acute regulatory protein as a target of endocrine disruption in male reproduction.Cross-talk between the Akt and NF-kappaB signaling pathways inhibits MEHP-induced germ cell apoptosis.Testicular dysgenesis syndrome and the origin of carcinoma in situ testis.Emerging endocrine disrupters: perfluoroalkylated substances.Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity: Lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates.Phthalate metabolism and kinetics in an in vitro model of testis development.A mixture of an environmentally realistic concentration of a phthalate and herbicide reduces testosterone in male fathead minnow (Pimephales promelas) through a novel mechanism of action.Challenges in the application of quantitative approaches in risk assessment: a case study with di-(2-ethylhexyl)phthalate.Toxicological review and oral risk assessment of terephthalic acid (TPA) and its esters: A category approach.Comparison of toxicogenomic responses to phthalate ester exposure in an organotypic testis co-culture model and responses observed in vivo.Human testis steroidogenesis is inhibited by phthalates.
P2860
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P2860
Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Gene expression profiling foll ...... logy of testicular dysgenesis.
@en
Gene expression profiling foll ...... logy of testicular dysgenesis.
@nl
type
label
Gene expression profiling foll ...... logy of testicular dysgenesis.
@en
Gene expression profiling foll ...... logy of testicular dysgenesis.
@nl
prefLabel
Gene expression profiling foll ...... logy of testicular dysgenesis.
@en
Gene expression profiling foll ...... logy of testicular dysgenesis.
@nl
P2093
P2860
P1476
Gene expression profiling foll ...... logy of testicular dysgenesis.
@en
P2093
Kevin W Gaido
Kim P Lehmann
Madhabananda Sar
S Stanley Young
P2860
P304
P356
10.1095/BIOLREPROD.104.039404
P407
P577
2005-02-23T00:00:00Z