Ser475, Glu272, Asp276, Asp327, and Asp360 are involved in catalytic activity of human tripeptidyl-peptidase I.
about
Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid LipofuscinosisA critical tryptophan and Ca2+ in activation and catalysis of TPPI, the enzyme deficient in classic late-infantile neuronal ceroid lipofuscinosisTripeptidyl-peptidase I in health and disease.The QM/MM molecular dynamics and free energy simulations of the acylation reaction catalyzed by the serine-carboxyl peptidase kumamolisin-As.Lysosomal serine protease CLN2 regulates tumor necrosis factor-alpha-mediated apoptosis in a Bid-dependent mannerNeuronal ceroid lipofuscinosis type CLN2: a new rationale for the construction of phenotypic subgroups based on a survey of 25 cases in South America.Prosegment of tripeptidyl peptidase I is a potent, slow-binding inhibitor of its cognate enzyme.A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation.
P2860
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P2860
Ser475, Glu272, Asp276, Asp327, and Asp360 are involved in catalytic activity of human tripeptidyl-peptidase I.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-hans
2005年学术文章
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2005年学术文章
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2005年學術文章
@yue
2005年學術文章
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name
Ser475, Glu272, Asp276, Asp327 ...... human tripeptidyl-peptidase I.
@en
Ser475, Glu272, Asp276, Asp327 ...... human tripeptidyl-peptidase I.
@nl
type
label
Ser475, Glu272, Asp276, Asp327 ...... human tripeptidyl-peptidase I.
@en
Ser475, Glu272, Asp276, Asp327 ...... human tripeptidyl-peptidase I.
@nl
prefLabel
Ser475, Glu272, Asp276, Asp327 ...... human tripeptidyl-peptidase I.
@en
Ser475, Glu272, Asp276, Asp327 ...... human tripeptidyl-peptidase I.
@nl
P2093
P2860
P1433
P1476
Ser475, Glu272, Asp276, Asp327 ...... human tripeptidyl-peptidase I.
@en
P2093
Adam A Golabek
Elizabeth Kida
Krystyna E Wisniewski
Mariusz Walus
P2860
P304
P356
10.1016/J.FEBSLET.2005.01.035
P407
P577
2005-02-01T00:00:00Z