The role of GTSE1 in G2/M progression after G2 checkpoint - Wikidata - wikimedia - TriplyDB

The role of GTSE1 in G2/M progression after G2 checkpoint

The role of GTSE1 in G2/M progression after G2 checkpoint

http://www.wikidata.org/entity/Q45314069

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GTSE1 binds microtubule lattice in interphase cells GTSE1 binds MAPRE1 (EB1) at microtubule plus ends Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends GTSE1 binds PLK1 PLK1 phosphorylates GTSE1 GTSE1 translocates to the nucleus GTSE1 binds CDKN1A

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G2/M Transition

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The role of GTSE1 in G2/M progression after G2 checkpoint

http://www.wikidata.org/entity/Q45314069

description

An instance of the biological ...... G2 checkpoint in Homo sapiens

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name

The role of GTSE1 in G2/M progression after G2 checkpoint

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type

label

The role of GTSE1 in G2/M progression after G2 checkpoint

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prefLabel

The role of GTSE1 in G2/M progression after G2 checkpoint

@en

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Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery

GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration

Human GTSE-1 regulates p21(CIP1/WAF1) stability conferring resistance to paclitaxel treatment.

Cell-cycle regulation of the p53-inducible gene B99.

The cell cycle-regulated protein human GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function.

hGTSE-1 expression stimulates cytoplasmic localization of p53.

A novel p53-inducible gene coding for a microtubule-localized protein with G2-phase-specific expression.

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reactome:R-HSA-8852276

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regulation of cell cycle G2/M phase transition

biological pathway

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G2/M Transition

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R-HSA-8852276

http://www.w3.org/2001/XMLSchema#string

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GTSE1 binds TP53

GTSE1 promotes translocation of TP53 to the cytosol

GTSE1 facilitates proteasome-mediated degradation of TP53

GTSE1 binds microtubule lattice in interphase cells

GTSE1 binds MAPRE1 (EB1) at microtubule plus ends

Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends

GTSE1 binds PLK1

PLK1 phosphorylates GTSE1

GTSE1 translocates to the nucleus

GTSE1 binds CDKN1A

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