Antigen Presentation: Folding, assembly and peptide loading of class I MHC
about
Binding of newly synthesized MHC class I heavy chain (HC) with calnexinInteraction of Erp57 with MHC class I HCInteraction of beta-2-microglobulin (B2M) chain with class I HCFormation of peptide loading complex (PLC)Transport of Antigen peptide in to ERTrimming of peptides in ERLoading of antigenic peptides on to class I MHCDissociation of the Antigenic peptide:MHC:B2M peptide loading complexTransport of MHC heterotrimer to ER exit siteCoat AssemblyCapturing cargo and formation of prebudding complexRecruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicleBudding of COPII coated vesicleDisassembly of COPII coated vesicleJourney of cargo through Golgi complexExpression of peptide bound class I MHC on cell surface
P361
Q50291521-17F1597E-6FB7-4BE4-971C-9909EC728B3DQ50291522-67565DE6-B447-496D-88EA-975C9C02AEDCQ50291523-8B7593B1-B13E-4745-8EB8-A0E8577FAF0CQ50291525-BBE19474-EA65-493F-8F6C-80F5E26A8494Q50291526-D8335A8F-70EA-46FE-8C95-1EADBEE146A8Q50291527-C472E726-DACA-4407-8410-1AE022B5A906Q50291528-7B1A6DC5-7340-4FB2-938E-DB45873BBFE1Q50291529-6E3BC7CD-8CE3-499B-92D4-05B952490774Q50291530-8524650E-EC76-4AFD-992B-FAB5FC5E75EAQ50291531-A574B316-3C4D-493F-A4AA-5264C071B0F0Q50291533-765015C6-3431-4A48-94C3-FE4F2AEE7CE6Q50291534-BFB0FF05-3BAE-4692-A15D-F290E93DC9B7Q50291535-55A32C85-5083-4E9C-A4AC-0D29FCDE4148Q50291536-E60E299F-DBA2-45A4-B09D-98833B9A338BQ50291537-856B3661-2CAC-4C45-96CD-39F1ABE630EEQ50291538-25B1266E-12C6-4C51-8D19-7DA243E4F991
P361
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
description
An instance of the biological ...... of class I MHC in Homo sapiens
@en
name
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
@en
type
label
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
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prefLabel
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
@en
P2860
P527
P2860
P3937
R-HSA-983170