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IL4R binds JAK2IL13RA1 binds TYK2IL4 binds IL4R:JAK2IL4:IL4R:JAK2 binds IL2RG:JAK3IL4:IL4R:JAK2 binds IL13RA1:TYK2JAK1 binds IL4R in IL4-bound IL4R1IL4R; IL2RG; JAK1 in IL4-bound IL4R1:JAK1 are phosphorylatedSTAT3;STAT6 bind p-Y-IL4RJAK1 phosphorylates STAT3;STAT6p-Y705-STAT3;p-Y641-STAT6 dissociatep-Y705-STAT3; p-Y641-STAT6 dimerisep-Y705-STAT3 dimer; p-Y641-STAT6 dimer translocate to nucleusExpression of SOCS1Expression of GATA3Expression of STAT6-upregulated extracellular proteinsExpression of STAT6-upregulated plasma membrane proteinsExpression of STAT3-upregulated extracellular proteinsExpression of STAT3-upregulated plasma membrane proteinsExpression of STAT3-upregulated cytosolic proteinsExpression of STAT3-upregulated nuclear proteinsExpression of BCL2; BCL2L1Expression of HSP90B1Expression of PTGS2Expression of NDN;TP53Expression of FASLGSOCS5;(SOCS1) bind IL4RAIL13 binds IL13RA2IL13 binds IL13RA:TYK2IL13:IL13RA:TYK2 binds IL4R:JAK2JAK1 binds IL4R in IL13-bound IL13R type IIIL4R; IL13RA; JAK2 and TYK2 are tyrosine phosphorylatedSTAT1;STAT3;STAT6 bind IL13:IL13R type IISTAT1;STAT3;STAT6 phosphorylationp-Y-STATs dissociatep-Y-STATs dimerizep-Y-STATs translocate to nucleusExpression of IL4; IL13-upregulated extracellular proteinsExpression of HSPA8; ALOX15Expression of CD36Expression of HMOX1
P361
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P361
description
An instance of the biological ...... n-13 signaling in Homo sapiens
@en
name
Interleukin-4 and Interleukin-13 signaling
@en
type
label
Interleukin-4 and Interleukin-13 signaling
@en
prefLabel
Interleukin-4 and Interleukin-13 signaling
@en
P527
P2860
P3937
R-HSA-6785807