about
Phosphate bond hydrolysis by NUDT proteinsNT5E:Zn2+ hydrolyses AMP;dAMP;GMP; IMP(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2)AMP + H2O => adenosine + orthophosphate(d)AMP; (d)GMP; or (d)IMP + H2O => (deoxy)adenosine; (deoxy)guanosine; or (deoxy)inosine + orthophosphate (NT5C1A)(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)DNPH1 hydrolyses dGMP(deoxy)guanosine + orthophosphate <=> guanine + (deoxy)ribose 1-phosphate (NP)(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate (NP)Guanine + H2O => Xanthine + NH4+Hypoxanthine + H2O + O2 => Xanthine + H2O2Xanthine + H2O + O2 => Urate + H2O2ITPA hydrolyses ITP to IMPITPA hydrolyses XTP to XMPITPA hydrolyses dITP to dIMP
P361
Q45317398-20D91DFB-2454-44E8-9671-D23BA68FC9D7Q50294632-D0A1E047-380F-4F8C-9AB3-5CF8295E738BQ50294633-CF9C78D1-EB63-4A39-B624-FA59E15CF5B6Q50294634-5C1AE22C-EE96-46CA-9F15-807C1B1D8703Q50294636-0BBD2D01-6624-48F7-98E5-A567960D5272Q50294637-07999B46-2955-4D65-815E-412F7F8EBC00Q50294639-28CA18ED-F5C5-4279-8AFD-618F6A7E6A1FQ50294640-2030BC68-2321-4668-A5FC-57E64F363E04Q50294641-B60C2D3C-DF76-47EB-B592-4E564ACB2466Q50294642-E606F6DD-1374-4A7F-BF93-C104FFA0E34CQ50294643-20A92B9C-522E-40AD-AE8C-5F3CA6CA69ACQ50294644-8AA70625-EDAC-4AA8-A1BF-F173859CB90CQ50294663-E4E4AF42-5D04-4694-BAA4-C101F1C18861Q50294665-E1D75083-E822-4AA5-8DEC-04DA4D096BF8Q50294666-90ACD9AD-E40B-4E14-A238-F20D7E39C642
P361
description
An instance of the biological pathway Purine catabolism in Homo sapiens
@en
name
Purine catabolism
@en
type
label
Purine catabolism
@en
prefLabel
Purine catabolism
@en
P527
P2888
P3937
R-HSA-74259