Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA - Wikidata - wikimedia - TriplyDB

Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

http://www.wikidata.org/entity/Q45317563

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Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA BRF1 Complex recruits RNA degradation activities Protein Kinase B/Akt phosphorylates BRF1 MK2 phosphorylates BRF1 p-S92;203-BRF1 binds 14-3-3 p-S54;92;203-BRF1 binds 14-3-3

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Regulation of mRNA stability by proteins that bind AU-rich elements

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Q45317561-8612BC91-9F69-4ED2-BC28-799B775E87E8

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Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

http://www.wikidata.org/entity/Q45317563

description

An instance of the biological ...... tabilizes mRNA in Homo sapiens

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name

Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

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type

label

Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

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prefLabel

Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

@en

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

AU-rich elements and associated factors: are there unifying principles?

Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1

AU-rich element-mediated translational control: complexity and multiple activities of trans-activating factors.

Post-transcriptional regulation of gene expression by degradation of messenger RNAs.

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reactome:R-HSA-450385

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regulation of mRNA stability

biological pathway

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Regulation of mRNA stability by proteins that bind AU-rich elements

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R-HSA-450385

http://www.w3.org/2001/XMLSchema#string

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Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA

BRF1 Complex recruits RNA degradation activities

Protein Kinase B/Akt phosphorylates BRF1

MK2 phosphorylates BRF1

p-S92;203-BRF1 binds 14-3-3

p-S54;92;203-BRF1 binds 14-3-3

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