A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling.
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Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous CapMolecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models.The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture.Elastin fragmentation in atherosclerotic mice leads to intraplaque neovascularization, plaque rupture, myocardial infarction, stroke, and sudden death.A Unique Recombinant Fluoroprobe Targeting Activated Platelets Allows In Vivo Detection of Arterial Thrombosis and Pulmonary Embolism Using a Novel Three-Dimensional Fluorescence Emission Computed Tomography (FLECT) Technology.Atorvastatin improves plaque stability in ApoE-knockout mice by regulating chemokines and chemokine receptors.Near-infrared autofluorescence induced by intraplaque hemorrhage and heme degradation as marker for high-risk atherosclerotic plaques.Raised soluble P-selectin moderately accelerates atherosclerotic plaque progressionDistinct gene signatures in aortic tissue from ApoE-/- mice exposed to pathogens or Western diet.Targeting blood thrombogenicity precipitates atherothrombotic events in a mouse model of plaque destabilizationAtherosclerotic Plaque Destabilization in Mice: A Comparative StudyNatural progression of atherosclerosis from pathologic intimal thickening to late fibroatheroma in human coronary arteries: A pathology study.Prediction of acute coronary syndromes by urinary proteome analysis.Identification of novel genes and pathways in carotid atheroma using integrated bioinformatic methodsLoss of ADAMTS4 reduces high fat diet-induced atherosclerosis and enhances plaque stability in ApoE(-/-) mice.CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.Inflammation and plaque vulnerability.Angiogenesis in the atherosclerotic plaque.A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes.Signaling events in pathogen-induced macrophage foam cell formation.miRNAs in atherosclerotic plaque initiation, progression, and rupture.Role of biomechanical forces in the natural history of coronary atherosclerosis.Biomechanical factors in atherosclerosis: mechanisms and clinical implications.Cytotoxic lymphocytes and atherosclerosis: significance, mechanisms and therapeutic challenges.Selective endothelin A receptor antagonism with sitaxentan reduces neointimal lesion size in a mouse model of intraluminal injuryDistinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot studyAnti-atherosclerotic effect of the angiotensin 1-7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis.Polymer Capsules for Plaque-Targeted In Vivo Delivery.MiR-181b Antagonizes Atherosclerotic Plaque Vulnerability Through Modulating Macrophage Polarization by Directly Targeting Notch1.Knockdown of microRNA-17-5p ameliorates atherosclerotic lesions in ApoE-/- mice and restores the expression of very low density lipoprotein receptor.Temporal and spatial changes in wall shear stress during atherosclerotic plaque progression in mice.Elevated levels of 2-arachidonoylglycerol promote atherogenesis in ApoE-/- mice.Circulating miRNA levels differ with respect to carotid plaque characteristics and symptom occurrence in patients with carotid artery stenosis and provide information on future cardiovascular events.Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosisDestination Known: Targeted Drug Delivery in Atherosclerosis and ThrombosisMicroRNAs and cardiovascular diseases
P2860
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P2860
A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
A novel mouse model of atheros ...... microRNA expression profiling.
@en
A novel mouse model of atheros ...... microRNA expression profiling.
@nl
type
label
A novel mouse model of atheros ...... microRNA expression profiling.
@en
A novel mouse model of atheros ...... microRNA expression profiling.
@nl
prefLabel
A novel mouse model of atheros ...... microRNA expression profiling.
@en
A novel mouse model of atheros ...... microRNA expression profiling.
@nl
P2093
P50
P1433
P1476
A novel mouse model of atheros ...... microRNA expression profiling.
@en
P2093
Alex Agrotis
Alex Bobik
Anh Viet Bui
Christian Hausding
Izhak Haviv
Jennifer Rivera
Jeremy Jowett
Nay Min Htun
Richard Manasseh
Yung-Chih Chen
P304
P356
10.1161/CIRCRESAHA.113.301562
P577
2013-06-07T00:00:00Z