A mechanism of sialylation functionally silences the hyaluronan receptor LYVE-1 in lymphatic endothelium.
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Biology of hyaluronan: Insights from genetic disorders of hyaluronan metabolismHomodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic EndotheliumN-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronanA hyaluronan receptor for endocytosis (HARE) link domain N-glycan is required for extracellular signal-regulated kinase (ERK) and nuclear factor-κB (NF-κB) signaling in response to the uptake of hyaluronan but not heparin, dermatan sulfate, or acetyTerminal sialic acids on CD44 N-glycans can block hyaluronan binding by forming competing intramolecular contacts with arginine sidechains.The interaction between LYVE-1 with hyaluronan on the cell surface may play a role in the diversity of adhesion to cancer cells.Low molecular weight hyaluronan induces lymphangiogenesis through LYVE-1-mediated signaling pathwaysSyndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148Proinflammatory signals and the loss of lymphatic vessel hyaluronan receptor-1 (LYVE-1) in the early pathogenesis of laminin alpha2-deficient skeletal muscle.Revealing the Mechanisms of Protein Disorder and N-Glycosylation in CD44-Hyaluronan Binding Using Molecular SimulationRapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 InteractionNEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does notCritical importance of appropriate fixation conditions for faithful imaging of receptor microclusters.Characterization of cells expressing lymphatic marker LYVE-1 in macaque large intestine during simian immunodeficiency virus infection identifies a large population of nonvascular LYVE-1(+)/DC-SIGN(+) cellsBinding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan OrganizationLymphatic Regulation of Cellular TraffickingChain gangs: new aspects of hyaluronan metabolism.Distinctive properties of the hyaluronan-binding domain in the lymphatic endothelial receptor Lyve-1 and their implications for receptor function.Neutrophils rapidly transit inflamed lymphatic vessel endothelium via integrin-dependent proteolysis and lipoxin-induced junctional retraction.Histological study and LYVE-1 immunolocalization of mouse mesenteric lymph nodes with "In Vivo Cryotechnique".TGFβ counteracts LYVE-1-mediated induction of lymphangiogenesis by small hyaluronan oligosaccharides.Inflammation-driven dermal lymphangiogenesis in atopic dermatitis is associated with CD11b+ macrophage recruitment and VEGF-C up-regulation in the IL-4-transgenic mouse model.
P2860
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P2860
A mechanism of sialylation functionally silences the hyaluronan receptor LYVE-1 in lymphatic endothelium.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
A mechanism of sialylation fun ...... VE-1 in lymphatic endothelium.
@en
A mechanism of sialylation fun ...... VE-1 in lymphatic endothelium.
@nl
type
label
A mechanism of sialylation fun ...... VE-1 in lymphatic endothelium.
@en
A mechanism of sialylation fun ...... VE-1 in lymphatic endothelium.
@nl
prefLabel
A mechanism of sialylation fun ...... VE-1 in lymphatic endothelium.
@en
A mechanism of sialylation fun ...... VE-1 in lymphatic endothelium.
@nl
P2093
P2860
P356
P1476
A mechanism of sialylation fun ...... YVE-1 in lymphatic endothelium
@en
P2093
David G Jackson
Matthew E F Frayne
Steven Clasper
Suneale Banerji
P2860
P304
P356
10.1074/JBC.M805105200
P407
P577
2008-11-25T00:00:00Z