about
CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infectionHuman CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivoMemory T cell homeostasis and senescence during aging.Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1Increased expression of Tbet in CD4(+) T cells from clinically isolated syndrome patients at high risk of conversion to clinically definite MS.Dose-related effects of vitamin D on immune responses in patients with clinically isolated syndrome and healthy control participants: study protocol for an exploratory randomized double- blind placebo-controlled trialT cells in multiple sclerosis and experimental autoimmune encephalomyelitis.Therapeutic use of vitamin D and its analogues in autoimmunity.Hidradenitis suppurativa is characterised by dysregulation of the Th17:Treg cell axis, which is corrected by anti-TNF therapy.Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells.The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome.Suppression of human alloreactive T cells by linear tetrapyrroles; relevance for transplantation.Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo.Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta.CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis.Epstein-Barr virus-specific CD8(+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential.Progressive telomere shortening of Epstein-Barr virus-specific memory T cells during HIV infection: contributor to exhaustion?Response to comment on the article by Allen et al. 'A pilot study of the immunological effects of high-dose vitamin D in healthy volunteers'.A pilot study of the immunological effects of high-dose vitamin D in healthy volunteers.Impact of CMV and EBV seropositivity on CD8 T lymphocytes in an old population from West-Sicily.Quiescence and functional reprogramming of Epstein-Barr virus (EBV)-specific CD8+ T cells during persistent infection.Integration of apoptosis and telomere erosion in virus-specific CD8+ T cells from blood and tonsils during primary infection.The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion.Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.OAS1: a multiple sclerosis susceptibility gene that influences disease severity.Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell-Mediated Suppression in the Context of Autoimmunity.Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo.Altered metabolic pathways regulate synovial inflammation in Rheumatoid ArthritisThe pathogenic role of dendritic cells in non-infectious anterior uveitisIL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cellsThe Biology of Multiple SclerosisEnriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesisNatural killer cell lysis of cytomegalovirus (CMV)-infected cells correlates with virally induced changes in cell surface lymphocyte function-associated antigen-3 (LFA-3) expression and not with the CMV-induced down-regulation of cell surface class IIn vivo and vitro in diagnosis of latex allergy at Groote Schuur HospitalNaturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment.Targeting bioenergetics prevents CD4 T cell-mediated activation of synovial fibroblasts in rheumatoid arthritisEnrichment of Plasma Cells in the Peripheral Blood and Skin of Patients with Hidradenitis SuppurativaEnrichment of polyfunctional IL-17 producing T cells in paradoxical psoriasis skin lesions
P50
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P50
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wetenschapper
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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Jean M. Fletcher
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lccn-no2017046266