Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
about
A comparative analysis of the aggregation behavior of amyloid-β peptide variantsImpact of apolipoprotein E on Alzheimer's diseaseTargeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeuticsTransient dynamics of Aβ contribute to toxicity in Alzheimer's diseaseDye-binding assays for evaluation of the effects of small molecule inhibitors on amyloid (aβ) self-assemblyCharacteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet MimicsTowards a Pharmacophore for AmyloidCrystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomersMolecular basis for amyloid- polymorphismOut-of-register -sheets suggest a pathway to toxic amyloid aggregatesX-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Aβ 17–36A Fibril-Like Assembly of Oligomers of a Peptide Derived from β-AmyloidNMR structure of the water soluble Aβ17-34 peptideProtein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitusAmyloid-β protofibrils: size, morphology and synaptotoxicity of an engineered mimicEngineering amyloid-like assemblies from unstructured peptides via site-specific lipid conjugationMonoclonal antibodies against Aβ42 fibrils distinguish multiple aggregation state polymorphisms in vitro and in Alzheimer disease brain.Efficient molecular mechanics simulations of the folding, orientation, and assembly of peptides in lipid bilayers using an implicit atomic solvation model.Analysis of the stabilities of hexameric amyloid-β(1-42) models using discrete molecular dynamics simulationsBeta-barrel models of soluble amyloid beta oligomers and annular protofibrils.Silk fibroin-derived nanoparticles for biomedical applications.Recent progress in understanding Alzheimer's β-amyloid structures.Antiparallel triple-strand architecture for prefibrillar Aβ42 oligomersTechniques for Monitoring Protein Misfolding and Aggregation in Vitro and in Living CellsAlzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal.Quantifying prefibrillar amyloids in vitro by using a "thioflavin-like" spectroscopic method.Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction.Calcium ions promote formation of amyloid β-peptide (1-40) oligomers causally implicated in neuronal toxicity of Alzheimer's disease.Polymorphic structures of Alzheimer's β-amyloid globulomers.Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease.A yeast toxic mutant of HET-s((218-289)) prion displays alternative intermediates of amyloidogenesisStabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineeringIdentification of peptides derived from the human antimicrobial peptide LL-37 active against biofilms formed by Pseudomonas aeruginosa using a library of truncated fragments.Dominance of misfolded intermediates in the dynamics of α-helix foldingModeling amyloid-beta as homogeneous dodecamers and in complex with cellular prion protein.Conformational stability of fibrillar amyloid-beta oligomers via protofilament pair formation - a systematic computational studyStructural similarities and differences between amyloidogenic and non-amyloidogenic islet amyloid polypeptide (IAPP) sequences and implications for the dual physiological and pathological activities of these peptides.Insight into amyloid structure using chemical probes.Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.Antiparallel β-Sheet Structure within the C-Terminal Region of 42-Residue Alzheimer's Amyloid-β Peptides When They Form 150-kDa Oligomers.
P2860
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P2860
Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
@en
Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
@nl
type
label
Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
@en
Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
@nl
prefLabel
Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
@en
Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
@nl
P2093
P50
P356
P1433
P1476
Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide.
@en
P2093
Emilie Cerf
Erik Goormaghtigh
Jean-Marie Ruysschaert
Rabia Sarroukh
Shiori Tamamizu-Kato
Sylvie Derclaye
Vasanthy Narayanaswami
Vincent Raussens
P304
P356
10.1042/BJ20090379
P407
P577
2009-07-15T00:00:00Z