Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.
about
Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liverThe enigmatic X gene of hepatitis B virusViruses associated with human cancerHBx M130K and V131I (T-A) mutations in HBV genotype F during a follow-up study in chronic carriers.Hepatitis B virus, HBx mutants and their role in hepatocellular carcinomaHepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2The role of the hepatitis viruses in cholangiocarcinomaCytochrome C oxidase III interacts with hepatitis B virus X protein in vivo by yeast two-hybrid system.Transfection and expression of hepatitis B virus x gene and its effect on apoptosis in HL-7702 cells.A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthaseSignificance of viral status on occurrence of hepatitis B-related hepatocellular carcinoma.Clinical implications of hepatitis B virus mutations: recent advances.Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein.Molecular Pathogenesis of Hepatitis-B-virus-associated Hepatocellular Carcinoma.Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma developmentHepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patientsParacrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesisInteraction of Hepatitis B virus with cellular processes in liver carcinogenesis.Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line.Apoptosis in diseases of the liver.Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytesThe effect of miR-338-3p on HBx deletion-mutant (HBx-d382) mediated liver-cell proliferation through CyclinD1 regulationThe hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage.Genetic mechanisms of hepatocarcinogenesis.Hepatoma cell line HepG2.2.15 demonstrates distinct biological features compared with parental HepG2.Viral determinants and host immune responses in the pathogenesis of HBV infection.Hepatitis B virus X protein enhances cisplatin-induced hepatotoxicity via a mechanism involving degradation of Mcl-1.Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB.Technical standards for hepatitis B virus X protein (HBx) research.European multicenter evaluation of high-density DNA probe arrays for detection of hepatitis B virus resistance mutations and identification of genotypesMolecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview.Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis.Modulation of apoptosis as a target for liver disease.Influence of hepatitis B virus X and core promoter mutations on hepatocellular carcinoma among patients infected with subgenotype C2.Discovery of a Novel Mutation (X8Del) Resulting in an 8-bp Deletion in the Hepatitis B Virus X Gene Associated with Occult Infection in Korean Vaccinated Individuals.Biological impacts of "hot-spot" mutations of hepatitis B virus X proteins are genotype B and C differentiatedAggregate formation of hepatitis B virus X protein affects cell cycle and apoptosis.Anti-hepatitis B virus (HBV) response of imiquimod based toll like receptor 7 ligand in hbv-positive human hepatocelluar carcinoma cell line.Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction.The molecular diagnosis of hepatitis B virus-associated hepatocellular carcinoma.
P2860
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P2860
Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Hepatitis B virus X mutants, p ...... ransactivation effects of HBx.
@en
Hepatitis B virus X mutants, p ...... ransactivation effects of HBx.
@nl
type
label
Hepatitis B virus X mutants, p ...... ransactivation effects of HBx.
@en
Hepatitis B virus X mutants, p ...... ransactivation effects of HBx.
@nl
prefLabel
Hepatitis B virus X mutants, p ...... ransactivation effects of HBx.
@en
Hepatitis B virus X mutants, p ...... ransactivation effects of HBx.
@nl
P2093
P2860
P356
P1433
P1476
Hepatitis B virus X mutants, p ...... ransactivation effects of HBx.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202867
P407
P577
1999-08-01T00:00:00Z
P5875
P6179
1014813589