Mapping loci influencing the persistence of Theiler's virus in the murine central nervous system.
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Theiler's virus infection: a model for multiple sclerosisGenetic Control of Neuroadapted Sindbis Virus Replication in Female Mice Maps to Chromosome 2 and Associates with Paralysis and MortalityTheiler's virus infection induces a predominant pathogenic CD4+ T cell response to RNA polymerase in susceptible SJL/J miceRole of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response.H-2D(b-/-) mice are susceptible to persistent infection by Theiler's virusViral load and a locus on chromosome 11 affect the late clinical disease caused by Theiler's virusNeuroimmune interactions in a model of multiple sclerosis.Viral load increases in SJL/J mice persistently infected by Theiler's virus after inactivation of the beta(2)m gene.Multiple loci govern the bone marrow-derived immunoregulatory mechanism controlling dominant resistance to autoimmune orchitisCapsid-specific cytotoxic T lymphocytes recognize three distinct H-2D(b)-restricted regions of the BeAn strain of Theiler's virus and exhibit different cytokine profilesThe majority of infiltrating CD8+ T cells in the central nervous system of susceptible SJL/J mice infected with Theiler's virus are virus specific and fully functional.Bone marrow chimeras reveal non-H-2 hematopoietic control of susceptibility to Theiler's virus persistent infectionTwo loci, Tmevp2 and Tmevp3, located on the telomeric region of chromosome 10, control the persistence of Theiler's virus in the central nervous system of mice.Sex-specific quantitative trait loci govern susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinationPreferential induction of protective T cell responses to Theiler's virus in resistant (C57BL/6 x SJL)F1 miceTmevpg1, a candidate gene for the control of Theiler's virus persistence, could be implicated in the regulation of gamma interferon.The level of viral infection of antigen-presenting cells correlates with the level of development of Theiler's murine encephalomyelitis virus-induced demyelinating disease.Evidence for the genetic control of estradiol-regulated responses. Implications for variation in normal and pathological hormone-dependent phenotypesEarly infection of the central nervous system by the GDVII and DA strains of Theiler's virus.Gamma interferon is critical for resistance to Theiler's virus-induced demyelination.The shiverer mutation affects the persistence of Theiler's virus in the central nervous systemTheiler's virus and Mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL/6 mice.Cytotoxic T-cell-resistant variants arise at early times after infection in C57BL/6 but not in SCID mice infected with a neurotropic coronavirus.The immune system preferentially clears Theiler's virus from the gray matter of the central nervous system.Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseasesDeficient Natural Killer Dendritic Cell Responses Underlay the Induction of Theiler's Virus-Induced Autoimmunity.Decoding the noncoding: prospective of lncRNA-mediated innate immune regulationTheiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors.Long noncoding RNAs in diseases of aging.The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locusChimeric Theiler's virus with altered tropism for the central nervous systemFVB mice transgenic for the H-2Db gene become resistant to persistent infection by Theiler's virus.Gene regulation in the immune system by long noncoding RNAs.Evidence for linkage and association between autoimmune thyroid diseases and the 18q12-q21 region in a large Tunisian family.Multiple sclerosis: multiple etiologies, multiple genes?The infection of mouse by Theiler's virus: from genetics to immunology.Antiviral immune responses modulate the nature of central nervous system (CNS) disease in a murine model of multiple sclerosis.V(beta)8(+) T cells protect from demyelinating disease in a viral model of multiple sclerosis.Genetics of susceptibility to Theiler's virus infection.A hybrid between a resistant and a susceptible strain of mouse alters the pattern of Theiler's murine encephalomyelitis virus-induced white matter disease and favors oligodendrocyte-mediated remyelination.
P2860
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P2860
Mapping loci influencing the persistence of Theiler's virus in the murine central nervous system.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
Mapping loci influencing the p ...... murine central nervous system.
@en
Mapping loci influencing the p ...... murine central nervous system.
@nl
type
label
Mapping loci influencing the p ...... murine central nervous system.
@en
Mapping loci influencing the p ...... murine central nervous system.
@nl
prefLabel
Mapping loci influencing the p ...... murine central nervous system.
@en
Mapping loci influencing the p ...... murine central nervous system.
@nl
P2093
P356
P1433
P1476
Mapping loci influencing the p ...... murine central nervous system.
@en
P2093
P2888
P356
10.1038/NG0993-87
P407
P577
1993-09-01T00:00:00Z
P6179
1040726117