Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
about
New developments in the management of moderate-to-severe hemophilia BEmerging and future therapies for hemophiliaFusion Proteins for Half-Life Extension of Biologics as a Strategy to Make BiobettersAchieving and maintaining an optimal trough level for prophylaxis in haemophilia: the past, the present and the futureFc-fusion technology and recombinant FVIII and FIX in the management of the hemophiliasOnce-weekly prophylactic dosing of recombinant factor IX improves adherence in hemophilia BAspects of prophylactic treatment of hemophiliaExtravascular FIX and coagulationThe neonatal Fc receptor, FcRn, as a target for drug delivery and therapyThe History of Clotting Factor Concentrates PharmacokineticsHemophilia Care in the Pediatric Age.Clinical utility and patient perspectives on the use of extended half-life rFIXFc in the management of hemophilia B.Management of hemophilia in Korea: the past, present, and future.Recombinant long-acting glycoPEGylated factor IX in hemophilia B: a multinational randomized phase 3 trialRegulation of immune responses by the neonatal fc receptor and its therapeutic implicationsAAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice.Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies.Issues in assessing products for the treatment of hemophilia - the intersection between efficacy, economics, and ethics.Recombinant Factor IX Fc Fusion Protein Maintains Full Procoagulant Properties and Exhibits Prolonged Efficacy in Hemophilia B Mice.Long-acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: results of a phase 3 trial.Physical activity in individuals with haemophilia and experience with recombinant factor VIII Fc fusion protein and recombinant factor IX Fc fusion protein for the treatment of active patients: a literature review and case reports.Human cell lines for biopharmaceutical manufacturing: history, status, and future perspectives.Prophylactic efficacy of BeneFIX vs Alprolix in hemophilia B mice.Novel products for haemostasis - current status.Changing paradigm of prophylaxis with longer acting factor concentrates.Emerging drugs for hemophilia B.Current management of hemophilia B: recommendations, complications and emerging issues.Research in haemophilia B--approaching the request for high evidence levels in a rare disease.Individualizing prophylaxis in hemophilia: a review.Role of enhanced half-life factor VIII and IX in the treatment of haemophilia.The current status of prophylactic replacement therapy in children and adults with haemophilia.Longer-acting clotting factor concentrates for hemophilia.A systematic review of definitions and reporting of bleeding outcome measures in haemophilia.New and Emerging Agents for the Treatment of Hemophilia: Focus on Extended Half-Life Recombinant Clotting Proteins.Health-related quality of life assessment in haemophilia patients on prophylaxis therapy: a systematic review of results from prospective clinical trials.New products for the treatment of haemophilia.Eftrenonacog Alfa: A Review in Haemophilia B.Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model.Current and future prospects for hemophilia gene therapy.Haemophilia treatment in 2030.
P2860
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P2860
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
@en
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
@nl
type
label
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
@en
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
@nl
prefLabel
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
@en
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
@nl
P2093
P921
P356
P1476
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
@en
P2093
Alison Innes
Aoife Brennan
B-LONG Investigators
David Perry
Glenn F Pierce
Gloria Vigliani
Godfrey C Chan
Haiyan Jiang
Jaya Goyal
P304
P356
10.1056/NEJMOA1305074
P407
P577
2013-12-04T00:00:00Z