Long-term engraftment of single genetically modified human epidermal holoclones enables safety pre-assessment of cutaneous gene therapy.
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Feeder Layer Cell Actions and ApplicationsGene therapy for skin diseasesCapturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancerBiosafety assessment of site-directed transgene integration in human umbilical cord-lining cells.Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin graftsA single epidermal stem cell strategy for safe ex vivo gene therapy.Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expressionPreclinical corrective gene transfer in xeroderma pigmentosum human skin stem cells.Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB.Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombinationStem cells and tissue-engineered skin.ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection.Gene editing for skin diseases: designer nucleases as tools for gene therapy of skin fragility disorders.Enhanced regulation of cell cycle and suppression of osteoblast differentiation molecular signatures by prostate cancer stem-like holoclones.Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes.Efficient KRT14 targeting and functional characterization of transplanted human keratinocytes for the treatment of epidermolysis bullosa simplex.Long-term skin regeneration from a gene-targeted human epidermal stem cell cloneRisk assessment in skin gene therapy: viral-cellular fusion transcripts generated by proviral transcriptional read-through in keratinocytes transduced with self-inactivating lentiviral vectors.Keratinocyte cell lines derived from severe generalized recessive epidermolysis bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo.The regenerative potential of fibroblasts in a new diabetes-induced delayed humanised wound healing model.An RNA-targeted therapy for dystrophic epidermolysis bullosa.Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells.
P2860
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P2860
Long-term engraftment of single genetically modified human epidermal holoclones enables safety pre-assessment of cutaneous gene therapy.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Long-term engraftment of singl ...... ent of cutaneous gene therapy.
@en
Long-term engraftment of singl ...... ent of cutaneous gene therapy.
@nl
type
label
Long-term engraftment of singl ...... ent of cutaneous gene therapy.
@en
Long-term engraftment of singl ...... ent of cutaneous gene therapy.
@nl
prefLabel
Long-term engraftment of singl ...... ent of cutaneous gene therapy.
@en
Long-term engraftment of singl ...... ent of cutaneous gene therapy.
@nl
P2093
P50
P356
P1433
P1476
Long-term engraftment of singl ...... ent of cutaneous gene therapy.
@en
P2093
Fernando Larcher
Giovanna Zambruno
José L Jorcano
Laura Rico
Marcela Del Rio
Sergio Bondanza
P304
P356
10.1038/SJ.MT.6300238
P577
2007-06-19T00:00:00Z