Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.
about
Wilms' tumorigenesis is altered by misexpression of the transcriptional co-activator, CITED1Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreasTargeted destruction of the orchestration of the pancreatic stroma and tumor cells in pancreatic cancer cases: molecular basis for therapeutic implicationsSmad4-mediated TGF-beta signaling in tumorigenesis.miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer.Biological approaches to therapy of pancreatic cancer.Gene therapy in pancreatic cancer.Biology and management of pancreatic cancer.Transcriptional silencing of ETS-1 abrogates epithelial-mesenchymal transition resulting in reduced motility of pancreatic cancer cellsLoss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis.Mutant p53 promotes tumor cell malignancy by both positive and negative regulation of the transforming growth factor β (TGF-β) pathway.Pancreatic cancer stromal biology and therapy.ETS transcription factors: possible targets for cancer therapy.Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-β Signaling.Immunotherapy for pancreatic cancer - science driving clinical progress.Molecular mechanisms of pancreatic carcinogenesis.MicroRNA-301a-3p promotes pancreatic cancer progression via negative regulation of SMAD4.Molecular mechanisms of pancreatic cancer and potential targets of treatment.Targeting signal transduction in pancreatic cancer treatment.Inhibition of pancreatic carcinoma cell growth in vitro by DPC4 gene transfection.Molecular changes in pancreatic cancer.Clinicopathological significance of SMAD4 loss in pancreatic ductal adenocarcinomas: a systematic review and meta-analysis.SMAD4 and its role in pancreatic cancer.Smad4 Inhibits VEGF-A and VEGF-C Expressions via Enhancing Smad3 Phosphorylation in Colon Cancer.BRCA1 regulates transforming growth factor-β (TGF-β1) signaling through Gadd45a by enhancing the protein stability of Smad4.Emerging roles of the bone morphogenetic protein pathway in cancer: potential therapeutic target for kinase inhibition.Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.The TGF-β/Smad4 Signaling Pathway in Pancreatic Carcinogenesis and Its Clinical Significance.Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis.TGF-β Tumor Suppression through a Lethal EMT.Quantitative phosphoproteomics of transforming growth factor-β signaling in colon cancer cells.Smad4 inactivation promotes malignancy and drug resistance of colon cancer.Transcriptional silencing of ETS-1 efficiently suppresses angiogenesis of pancreatic cancer.ETS-1 and ETS-2 are upregulated in a transgenic mouse model of pigmented ocular neoplasm.Roles of Smads Family and Alternative Splicing Variants of Smad4 in Different Cancers
P2860
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P2860
Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Restoration of SMAD4 by gene t ...... ncreatic adenocarcinoma cells.
@en
Restoration of SMAD4 by gene t ...... ncreatic adenocarcinoma cells.
@nl
type
label
Restoration of SMAD4 by gene t ...... ncreatic adenocarcinoma cells.
@en
Restoration of SMAD4 by gene t ...... ncreatic adenocarcinoma cells.
@nl
prefLabel
Restoration of SMAD4 by gene t ...... ncreatic adenocarcinoma cells.
@en
Restoration of SMAD4 by gene t ...... ncreatic adenocarcinoma cells.
@nl
P2093
P2860
P50
P356
P1433
P1476
Restoration of SMAD4 by gene t ...... ancreatic adenocarcinoma cells
@en
P2093
Dan G Duda
Fuyuhiko Motoi
Hiroko Inoue
Liviu P Lefter
Makoto Sunamura
Seiki Matsuno
Tadaaki Yokoyama
Tadayoshi Abe
Toshimasa Yatsuoka
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206751
P407
P577
2003-10-01T00:00:00Z
P5875
P6179
1047177404