Systemic delivery of scAAV9 in fetal macaques facilitates neuronal transduction of the central and peripheral nervous systems.
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Perinatal systemic gene delivery using adeno-associated viral vectorsGlial promoter selectivity following AAV-delivery to the immature brain.Systemic gene delivery to the central nervous system using Adeno-associated virus.Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice.Reduced phenotypic severity following adeno-associated virus-mediated Fmr1 gene delivery in fragile X mice.Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier.Initial gene vector dosing for studying symptomatology of amyotrophic lateral sclerosis in non-human primates.The expression pattern of systemically injected AAV9 in the developing mouse retina is determined by ageSystemic AAVrh10 provides higher transgene expression than AAV9 in the brain and the spinal cord of neonatal miceSystemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates.Fetal Brain-directed AAV Gene Therapy Results in Rapid, Robust, and Persistent Transduction of Mouse Choroid Plexus EpitheliaTailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9.Novel Vector Design and Hexosaminidase Variant Enabling Self-Complementary Adeno-Associated Virus for the Treatment of Tay-Sachs Disease.The advent of AAV9 expands applications for brain and spinal cord gene delivery.Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques.Adenoassociated virus serotype 9-mediated gene therapy for x-linked adrenoleukodystrophy.In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson's disease.In Utero Transfer of Adeno-Associated Viral Vectors Produces Long-Term Factor IX Levels in a Cynomolgus Macaque Model.Transduction of the central nervous system after intracerebroventricular injection of adeno-associated viral vectors in neonatal and juvenile miceLong-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.
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P2860
Systemic delivery of scAAV9 in fetal macaques facilitates neuronal transduction of the central and peripheral nervous systems.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Systemic delivery of scAAV9 in ...... nd peripheral nervous systems.
@en
Systemic delivery of scAAV9 in ...... nd peripheral nervous systems.
@nl
type
label
Systemic delivery of scAAV9 in ...... nd peripheral nervous systems.
@en
Systemic delivery of scAAV9 in ...... nd peripheral nervous systems.
@nl
prefLabel
Systemic delivery of scAAV9 in ...... nd peripheral nervous systems.
@en
Systemic delivery of scAAV9 in ...... nd peripheral nervous systems.
@nl
P2093
P2860
P50
P356
P1433
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Systemic delivery of scAAV9 in ...... and peripheral nervous systems
@en
P2093
C N Mattar
J K Y Chan
M Choolani
P2860
P2888
P356
10.1038/GT.2011.216
P577
2012-01-26T00:00:00Z
P6179
1023223591