Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: effects on serum ghrelin and appetite-regulating genes.
about
Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob miceDisruption in the leptin-NPY link underlies the pandemic of diabetes and metabolic syndrome: new therapeutic approachesInteractions of gastrointestinal peptides: ghrelin and its anorexigenic antagonists.Hypothalamic leptin gene therapy prevents weight gain without long-term detrimental effects on bone in growing and skeletally mature female rats.Effects of increased hypothalamic leptin gene expression on ovariectomy-induced bone loss in rats.Obesity and the ageing brain: could leptin play a role in neurodegeneration?To subjugate NPY is to improve the quality of life and live longerLeptin in anorexia and cachexia syndrome.Treatment of human disease by adeno-associated viral gene transfer.Central leptin insufficiency syndrome: an interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions.Body mass influences cortical bone mass independent of leptin signalingPeripheral leptin regulates bone formationIncreased leptin expression selectively in the hypothalamus suppresses inflammatory markers CRP and IL-6 in leptin-deficient diabetic obese miceBenefits of leptin therapy in HIV patients.Hypothalamic leptin gene therapy reduces body weight without accelerating age-related bone loss.Hypothalamic Leptin Gene Therapy Reduces Bone Marrow Adiposity in ob/ob Mice Fed Regular and High-Fat Diets.Central leptin gene therapy ameliorates diabetes type 1 and 2 through two independent hypothalamic relays; a benefit beyond weight and appetite regulation.Pivotal role of leptin-hypothalamus signaling in the etiology of diabetes uncovered by gene therapy: a new therapeutic intervention?Adipokine gene expression in a novel hypothalamic neuronal cell line: resistin-dependent regulation of fasting-induced adipose factor and SOCS-3.High d(+)-fructose diet adversely affects testicular weight gain in weaning rats─protection by moderate d(+)-glucose diet.Leptin expression in hypothalamic PVN reverses dietary obesity and hyperinsulinemia but stimulates ghrelin.Central leptin gene therapy blocks ovariectomy-induced adiposity.Effects of hypothalamic leptin gene therapy on osteopetrosis in leptin-deficient mice.Not insulin but insulin sensitivity, leptin, and cortisol are major factors regulating serum acylated ghrelin level in healthy women.Molecular Therapy of Melanocortin-4-Receptor Obesity by an Autoregulatory BDNF Vector.Increased leptin expression in the dorsal vagal complex suppresses adiposity without affecting energy intake and metabolic hormones.Obesity gene therapy: Slimming immature rats
P2860
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P2860
Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: effects on serum ghrelin and appetite-regulating genes.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Long-term suppression of weigh ...... and appetite-regulating genes.
@en
Long-term suppression of weigh ...... and appetite-regulating genes.
@nl
type
label
Long-term suppression of weigh ...... and appetite-regulating genes.
@en
Long-term suppression of weigh ...... and appetite-regulating genes.
@nl
prefLabel
Long-term suppression of weigh ...... and appetite-regulating genes.
@en
Long-term suppression of weigh ...... and appetite-regulating genes.
@nl
P2093
P2860
P921
P1433
P1476
Long-term suppression of weigh ...... and appetite-regulating genes.
@en
P2093
Elena Beretta
Michael G Dube
Pushpa S Kalra
Satya P Kalra
P2860
P304
P356
10.1203/00006450-200208000-00010
P407
P577
2002-08-01T00:00:00Z
P5875
P6179
1005403997